15 documents found, page 1 of 2

Urine metabolomics during a legume diet intervention suggests altered metabolic...

Given the general increase in legume consumption worldwide, there is a need to characterize the resulting human metabolic adaptations in order to demonstrate potential legume diet/health relationships. A nuclear magnetic resonance (NMR) metabolomics urine study was carried out on a small cohort (n = 18) to characterize the excretory effects of a pilot longitudinal 8-week legume-based dietary intervention. Despi...

Impact of a legumes diet on the human gut microbiome articulated with fecal and...

Background & aims: Legumes intake is known to be associated with several health benefits the origins of which is still a matter of debate. This paper addresses a pilot small cohort to probe for metabolic aspects of the interplay between legumes intake, human metabolism and gut microbiota. Methods: Untargeted nuclear magnetic resonance (NMR) metabolomics of blood plasma and fecal extracts was carried out, in tan...

Bétulas sustentáveis

O princípio base que está na construção e dinamização deste projeto de desenvolvimento comunitário é a contribuição para os Objetivos de Desenvolvimento Sustentável da ONU (3º e 11º), relacionados com a saúde pública e o meio ambiente. Este teve como finalidade criar um plano de intervenção para limpeza e desinfeção da Urbanização das Bétulas, perspetivando melhorar a saúde pública e fortalecer o sentido de per...

Multisystem Inflammatory Syndrome-Adult: A Rare Presentation of Infection by SA...

Among the manifestations of COVID-19, we find multisystem inflammatory syndrome (MIS), characterized by a hyperinflammatory state in which multiorgan dysfunction occurs.   A 22-years-old woman came to the emergency department with dry cough, myalgias, rash and fever for 3 days. PCR for SARS-CoV-2 was positive. Admitted to hospital on day 5 of disease due to symptomatic worsening. She had lesions in erythematous...

Impact of prematurity on newborn urine: a metabolomics strategy to identify mar...

Impacto de uma intervenção no local de prescrição na escolha do antibiótico na ...

Introdução - O uso incorrecto dos antibióticos é um problema grave estando directamente relacionado com o aumento das resistências bacterianas. Os Programas de Apoio à Prescrição de Antimicrobianos  podem ter impacto significativo na escolha do antibiótico a prescrever. É objectivo deste trabalho medir o impacto de uma intervenção simples na prescrição de antibióticos no serviço de urgência pediátrico. Métodos ...

Patologia benigna da tiróide e cancro da mama

Objetivos primários: Estimar a prevalência de patologia benigna da tiroide em mulheres adultas e com antecedentes de Ca mama; Estimar a prevalência de patologia benigna da tiroide em mulheres adultas sob observação na Rede MS. Objetivo secundário: Comparar a prevalência de patologia benigna da tiroide nas mulheres com antecedentes de Ca mama com a prevalência de patologia benigna da tiroide estimada na populaçã...

Urine metabolomics and proteomics in prenatal health

No abstract available.

Metabolic profiling of maternal urine can aid clinical management of gestationa...

Introduction The clinical management of Gestational diabetes mellitus (GDM) would benefit from enhanced metabolic knowledge both at the time of diagnosis and during therapy. Objectives This work aimed at unveiling metabolic markers of GDM and of the subjects' response to therapy. Methods Urine NMR metabolomics was used with a variable selection methodology to reduce uninformative variability. The NMR data was a...

Newborn Urinary Metabolic Signatures of Prematurity and Other Disorders: A Case...

This work assesses the urinary metabolite signature of prematurity in newborns by nuclear magnetic resonance (NMR) spectroscopy, while establishing the role of possible confounders and signature specificity, through comparison to other disorders. Gender and delivery mode are shown to impact importantly on newborn urine composition, their analysis pointing out at specific metabolite variations requiring consider...