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Early-life exposure to MYCOtoxins and its impact on health – a case study

Alvito, P.; Assunção, R.; Bastos-Amador, P.; de Boevre, M.; Duarte, E.; Martins, C.; Serrenho, i.; Silva, I.; Visintin, L.; Ferreira, M.

Considering the potential impact on health and the scarce data available regarding early-life exposure to mycotoxins, earlyMYCO project (early-life exposure to MYCOtoxins and its impact on health) proposed to answer key questions: are pregnant women and infants until six months exposed to mycotoxins? Is this exposure a health threat? Does this early-life exposure influence the intestinal immune system developme...


Membrane technology for valorization of mango peel extracts

Macedo, Antónia; Gomes, Tânia; Ribeiro, Carlos; Moldão-Martins, M.; Duarte, E.; Alves, V.

Mango peel is rich in nutritional and functional compounds, such as carbohydrates, dietary fibers, proteins, and phenolic compounds, with high potential to be applied in the food industry. Most of the investigation about recovery of bioactive compounds from fruit bioproducts involves extraction techniques and further separation of target compounds. There is still a lack of information about the potential of mem...


Early-life exposure to aflatoxin B1 and associated effects on gut microbiota: p...

Silva, I.; Duarte, E.; Bastos-Amador, P.; Ferreira, M.; Assunção, R.; Salvador, C.; Caldeira, A.

Aflatoxin B1 (AFB1) produces acute or chronic deleterious health effects in humans and animals. Still, long-term effects derived from initial exposure in early life, a critical period for colonization and development of gut microbiota, has not been fully evaluated. Particularly, aflatoxins could impair gut microbiota and immunity settlement, as they have been proven to cross the placental barrier and can be fou...


Integration of membrane processes for by-product valorization to improve the ec...

Cambóias, Eunice; Duarte, E.; Macedo, Antónia; Bilau, José

Goat and second cheese whey from sheep’s milk are by-products of the manufacture of goat cheeses and whey cheeses from sheep. Due to their composition which, apart from water—about 92%—includes lactose, proteins, fat, and minerals, and the elevated volumes generated, these by-products constitute one of the main problems facing to cheese producers. Aiming to add value to those by-products, this study evaluates t...


Valorization of goat cheese whey through an integrated process of ultrafiltrati...

Azedo, David; Duarte, E.; Pereira, C.; Macedo, Antónia

Goat cheese whey is a co-product that comes from goat cheese manufacture. Due to its high organic load, adequate treatment is necessary before its disposal. Additionally, the recent growing interest in caprine products, attributed to their specific nutritional and nutraceutical characteristics, such as the lower allergenicity of their proteins and higher content of oligosaccharides, compared with bovine product...


Furosemide in water matrix: HPLC-UV method development and degradation studies,...

Machado, A.I.; Fragoso, R.; Dordio, A.V.M.N.B.; Duarte, E.

This study developed a method for furosemide quantification through high performance liquid chromatographic technique. Special attention was given to solute loss and storage stability due to furosemide’s low solubility and photosensitivity, respectively. The performance of Nylon and PVDF filters was tested in a 2 mg.L-1 furosemide solution. PVDF filters showed better recovery capacity and therefore are more sui...


Performance of Iris pseudacorus and Typha domingensis for furosemide removal in...

Machado, A.I.; Fragoso, R.; Dordio, A.V.; Duarte, E.

The potential of Iris pseudacorus and Typha domingensis to remove the pharmaceutical active compound (PhAC) Furosemide from a nutrient solution was assessed. Both plants were exposed to 2 mg L−1 of furosemide during 21 days and the removal of furosemide was monitored. Vessels without furosemide were also implemented as control systems for plants development. Likewise, unplanted vessels with furosemide were empl...


Membrane applications for lactose recovering

Monteiro, J.; Azedo, D.; Duarte, E.; Pereira, C.; Macedo, Antónia

Cheese whey, the co-product from cheese making processes, is a natural and cheap source of high value compounds, mainly proteins, small peptides, oligosaccharides, lactose, and minerals. Lactose is the main component (about 90%) of the dry extract of cheese whey. This carbohydrate has plenty of application in the food and pharmaceutical industries due to its relative low sweetening power, caloric value, and gly...


3rd HBM-PT Workshop on Human BioMonitoring in Portugal - earlyMYCO: assessing t...

Assunção, Ricardo; Alvito, Paula; Ferreira, M.; Bastos, P.; Nunes, C.; De Boevre, Marthe; Duarte, E.; Nunes, B.; Namorado, S.; Silva, S.; Pires, S.

Livro de resumos do 3rd HBM-PT Workshop on Human BioMonitoring in Portugal sob o tema “Risk Assessment”, abrangendo trabalhos em torno das seguintes temáticas: Exposição a produtos químicos e efeitos na saúde humana; Influência da mudança do ambiente na exposição humana a produtos químicos; Integração de dados de monitorização humana e ambiental; Tradução dos dados de biomonitorização humana em ações regulament...


earlyMYCO: assessing the risk associated to early-life exposure to mycotoxins

Assunção, Ricardo; Alvito, Paula; Ferreira, M.; Bastos, P.; Nunes, C.; De Boevre, Marthe; Duarte, E.; Nunes, B.; Namorado, S.; Silva, S.; Pires, S.

A number of health disorders has been associated to exposure to hazardous chemicals during the first 1000 days of life. Therefore, a proper risk assessment built on accurate data assumes particular im-portance to evaluate the potential impact that early-life exposure could represent in adulthood. Mycotox-ins are secondary fungal metabolites that might cause harmful effects in humans and animals. Recent studies ...


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