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Surgical site infection in clean and clean contaminated procedures in veterinar...

Duarte, Elsa; Russell, Alpizar-Jara; Lavrador, Catarina

Surgical site infection (SSI) increases morbidity and antimicrobial use. It is essential to assess antimicrobial practices, especially in clean and clean-contaminated surgeries (C/CCS), where their necessity is often debated. This study assessed perioperative practices and antimicrobial use in eight Portuguese veterinary facilities, alongside SSI monitoring


Genetic variants in the IFNGR2 locus associated with severe chronic Q fever

David, Susana; Castro, Liliana; Duarte, Elsa; Gaspar, Ulisses; Rodrigues, Maria Rosário da Costa; Cueto-Rojo, Maria Vanessa; Mendonça, Joana

Q fever is a highly contagious zoonosis capable of causing large outbreaks of important health and economic consequences. Host genetic factors are believed to influence the development of severe chronic Q fever following the infection by the etiological agent, Coxiella burnetii. Targetted next generation sequencing (NGS) was performed in a case-control genetic association study on 53 confirmed Q fever cases, in...


Disentangling wildlife–cattle interactions in multi-host tuberculosis scenarios...

Ferreira, Eduardo; Duarte, Elsa; Cunha, Mõnica Vieira; Mira, António; Santos, Sara Maria

Ecological interactions involving wildlife (wild mammals) and cattle Bos taurus are considered fundamental drivers of animal tuberculosis (TB) caused by Mycobacterium bovis at the wildlife–livestock interface. Despite recent insights about the role of direct and indirect interactions on TB dynamics, a mechanistic evaluation of studies addressing patterns of wildlife–cattle interaction at the global level is lac...


Exposição precoce a contaminantes alimentares e avaliação de risco-beneficio de...

Alvito, Paula; Duarte, Elsa; Ferreira, M.; Nunes, C.; Pires, S.; Martins, Carla; Assunção, R.

As escolhas alimentares influenciam diretamente a dieta bem como o aporte diário de nutrientes. A sensibilização e a capacitação dos cidadãos para escolhas alimentares mais saudáveis é também determinante para uma estratégia para a promoção da alimentação saudável. Os alimentos pelos quais optamos apresentam compostos com efeitos benéficos, no entanto, alguns podem apresentar potencial efeito negativo para a sa...


One Health Day - 3 de Novembro

Vilhena, Manuela; Capela, Fernando; Duarte, Elsa; Lavrador, Catarina; Costa, Bruno

Foram realizadas um conjunto de palestras subordinadas ao tema Uma Saúde, onde foram discutidos o conceito, o âmbito, dificuldades de implementação e apresentadas alguns exemplos praticos.


Determinants of the Sympatric Host-Pathogen Relationship in Tuberculosis

David, Susana; Mateus, A.R.A.; Duarte, Elsa; Albuquerque, José Maria; Portugal, Clara; Sancho, Luísa; Lavinha, João; Gonçalves, Guilherme

Major contributions from pathogen genome analysis and host genetics have equated the possibility of Mycobacterium tuberculosis co-evolution with its human host leading to more stable sympatric host–pathogen relationships. However, the attribution to either sympatric or allopatric categories depends on the resolution or grain of genotypic haracterization. We explored the influence on the sympatric host-pathogen ...


Bioaccessibility assessment of patulin and ochratoxin A in cereal and fruit bas...

Assunção, Ricardo; Martins, Carla; Duarte, Elsa; Alvito, Paula

People, animals and the environment can be exposed to multiple chemicals at once from a variety of sources, but current risk assessment is usually carried out on one chemical substance at a time. Mycotoxins are fungal natural contaminants commonly found in a variety of foods including baby foods and have been found in cereal and fruit based baby foods. In human health risk assessment, ingestion of food is consi...


Screening of mosquitoes as vectores of F. tularensis in Portugal

Carvalho, Carina Luísa; Zé-Zé, Líbia; Duarte, Elsa; Núncio, M Sofia; Lopes de Carvalho, Isabel

Background: Francisella tularensis subsp. holartica is the etiologic agent of type B tularemia, an emergent zoonosis that occurred recently in Portugal´s neighboring country Spain, where there was an outbreak in 2007.(1) This fact has propelled the research of this pathogen in Portugal. Mosquitoes Culex spp. and Aedes spp. are considered important vectors of the pathogen in Sweden(2) but in Portugal the presenc...


Bridging the gap between PCR detection of Mycobacterium tuberculosis complex an...

Duarte, Elsa; Paixão, Eleonora; David, Susana

The growing demand for rapid diagnosis of tuberculosis (TB) has led to the incorporation of nucleic acid amplification (NAA) tests in case definitions. The objective of this study was to evaluate the contribution of a real-time polymerase chain reaction (PCR) assay in providing a result predictive of a confirmed TB case. Respiratory and extra-pulmonary specimens (n = 308) were subjected to NAA, culture and smea...


Tuberculosis in mandrills at the Lisbon zoo

Amado, Alice; Albuquerque, Teresa; Duarte, Elsa; Gonçalves, António; Botelho, Ana; Fernandes, Teresa; Bernardino, Rui; Lapão, Narciso

We would like to report two tuberculosis cases in a group of 10 mandrill baboons (Mandrillus sphinx) at the Lisbon zoo. In early 2006, a 16-year-old female, brought in from France in 1998, started to show signs of apathy, coughing and weight loss. Identical clinical signs were observed shortly after, in its threeyear-old daughter.Tuberculosis in zoo animals is uncommon in Portugal. This case reinforces the need...


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