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Bone Marrow Langerhans Cell Histiocytosis in Association with Kasabach-Merritt ...

Serra, JT; Silva, R; Aldomiro, F; Duarte, FP

Langerhans cell histiocytosis is a rare haematological disorder with variable clinical findings and a high mortality rate. On the other hand, Kasabach-Merritt syndrome is of rare onset at adult age, requiring the simultaneous presentation of vascular lesion, thrombocytopenia, and consumptive coagulopathy. We present the first reported case of both diseases in a single patient and highlight the difficulties of d...


Pregnancy with anti-PP1Pk antibody managed with prednisolone and low-molecular-...

Nascimento, S; Rodrigues, M; Henriques, M; Duarte, FP; Barra, A; Matos, T

The anti-PP1Pk is a rare antibody associated with recurrent miscarriages, mainly in the first half of pregnancy. There seems to be a direct correlation between the antibody titer and risk of miscarriage. As this is a rare entity, few case reports have been published. The most frequently proposed therapeutic approaches are doublefiltration plasmapheresis and plasma exchange therapy. The rationale behind them is ...


Hemoperitoneu Como Forma de Apresentação de Carcinoma Hepatocelular. Contributo...

Fonseca, CR; Duarte, FP

Nos países europeus, o hemoperitoneu por ruptura de carcinoma hepatocelular (HCC) é muito raro. Apresentam-se dois casos clínicos de hemoperitoneu secundário a ruptura espontânea de carcinoma hepatocelular, em que a Tomografia Computorizada (TC) abdominal foi de primordial importância para o diagnóstico. A propósito faz-se revisão da literatura sobre os aspectos mais relevantes desta patologia.


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