22 documents found, page 1 of 3

Neuroprotective effects of cyanobacterial extracts

Neurodegenerative diseases (ND), namely Alzheimer’s disease (AD) affects millions of people worldwide. Despite their high incidence there is still no effective medical therapy. Cyanobacteria have been in the frontline of the search for therapies for ND. Several in silico, in vitro, and in vivo studies have provided support for the neuroprotective potential of cyanobacterial natural products, particularly in AD....

The neuroprotective role of cyanobacteria with focus on the anti-inflammatory a...

Neurodegenerative diseases are linked to the process of neurodegeneration. This can be caused by several mechanisms, including inflammation and accumulation of reactive oxygen species. Despite their high incidence, there is still no effective treatment or cure for these diseases. Cyanobacteria have been seen as a possible source for new compounds with anti-inflammatory and antioxidant potential, such as polysac...

Relatório de Ensino Clínico - Integração à Vida Profissional

O presente relatório surge, não só como instrumento de avaliação do Ensino Clínico- Integração à Vida Profissional, mas também como uma reflexão de todas as experiências que vivenciei no decorrer deste, que foi o meu último EC enquanto aluna de enfermagem. Um dos principais objetivos foi melhorar a minha prática clínica, através do enriquecimento pessoal e profissional. Este encontra-se dividido em três partes,...

Tracing the path between mushrooms and Alzheimer's disease-a literature review

Alzheimer's disease (AD) is well-known among neurodegenerative diseases for the decline of cognitive functions, making overall daily tasks difficult or impossible. The disease prevails as the most common form of dementia and remains without a well-defined etiology. Being considered a disease of multifactorial origin, current targeted treatments have only managed to reduce or control symptoms, and to date, only ...

Umbrella review on the possible use of Ivermectin in the treatment of COVID-19

The urgency to find treatment and prophylactic measures for COVID-19, motivated the use of drugs usually indicated in other pathologies, such as Ivermectin (commonly used as antiparasitic). The main objective of this study was to evaluate the potential use of ivermectin in the treatment of COVID-19, and to identify its mechanism of action and dosing regimen regarding this particular indication. To perform this ...

Tracing the path between mushrooms and Alzheimer’s Disease—a literature review

Alzheimer’s disease (AD) is well-known among neurodegenerative diseases for the decline of cognitive functions, making overall daily tasks difficult or impossible. The disease prevails as the most common form of dementia and remains without a well-defined etiology. Being considered a disease of multifactorial origin, current targeted treatments have only managed to reduce or control symptoms, and to date, only ...

Stalling the course of neurodegenerative diseases: could cyanobacteria constitu...

Neurodegenerative diseases (NDs) are characterized by progressive and irreversible neuronal loss, accompanied by a range of pathological pathways, including aberrant protein aggregation, altered energy metabolism, excitotoxicity, inflammation, and oxidative stress. Some of the most common NDs include Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Multiple Sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS)...

Surface-Directed Mineralization of Fibrous Collagen Scaffolds in Simulated Body...

Made available in DSpace on 2021-06-25T10:22:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-15; The use of polymer additives that stabilize fluidic amorphous calcium phosphate is key to obtaining intrafibrillar mineralization of collagen in vitro. On the other hand, this biomimetic approach inhibits the nucleation of mineral crystals in unconfined extrafibrillar spaces, that is, extrafibrillar min...

Reproducibility and validity of the mediterranean diet quality of the mediterra...

Acidentes domésticos - o perigo escondido nas nossas casas

Os acidentes domésticos são uma das principais causas de morte em idade pediátrica. Circunstâncias aparentemente inofensivas, associadas à curiosidade das crianças, podem levar a situações que põem em risco o seu bem-estar. É importante alertar e educar a família para a prevenção e atuação nestas situações, bem como procurar educar a criança para a segurança. Apresentamos o caso de uma criança de 4 anos, com en...