17 documents found, page 1 of 2
LipidTOX: A fatty acid-based index efficient for ecotoxicological studies with ...
Duarte, Bernardo; Feijão, Eduardo; Franzitta, Marco; Duarte, Irina A.; de Carvalho, Ricardo Cruz; Cabrita, Maria Teresa; Marques, João CarlosContaminants, when present above certain thresholds, can induce physiological constraints to organisms, namely diatoms, a model group representative of marine phytoplankton, triggering feedback mechanisms, such as changes in cell's fatty acid profiles, that can be used as biomarkers towards xenobiotic exposure. Having this in mind and considering the ecological relevance of diatom fatty acid profiles as well as...
Fluoxetine induces photochemistry-derived oxidative stress on Ulva lactuca
Feijão, Eduardo; Carvalho, Ricardo Cruz de; Duarte, Irina A.; Matos, Ana Rita; Cabrita, Maria Teresa; Utkin, Andrei B.; Caçador, IsabelEmerging pollutants impose a high degree of stress on marine ecosystems, compromising valuable resources, the planet and human health. Pharmaceutical residues often reachmarine ecosystems, and their input is directly related to human activities. Fluoxetine is an antidepressant, and one of the most prescribed selective serotonin reuptake inhibitors globally and has been detected in aquatic ecosystems in concentr...
LipidTOX: A fatty acid-based index efficient for ecotoxicological studies with ...
Duarte, Bernardo; Feijão, Eduardo; Franzitta, Marco; Duarte, Irina A.; Cruz De Carvalho, Ricardo; Cabrita, Maria Teresa; Marques, João CarlosContaminants, when present above certain thresholds, can induce physiological constraints to organisms, namely diatoms, a model group representative of marine phytoplankton, triggering feedback mechanisms, such as changes in cell’s fatty acid profiles, that can be used as biomarkers towards xenobiotic exposure. Having this in mind and considering the ecological relevance of diatom fatty acid profiles as well as...
LipidTOX: a fatty acid-based index efficient for ecotoxicological studies with ...
Duarte, Bernardo; Feijão, Eduardo; Franzitta, Marco; Duarte, Irina A.; de Carvalho, Ricardo Cruz; Cabrita, Maria Teresa; Marques, João CarlosContaminants, when present above certain thresholds, can induce physiological constraints to organisms, namely diatoms, a model group representative of marine phytoplankton, triggering feedback mechanisms, such as changes in cell’s fatty acid profiles, that can be used as biomarkers towards xenobiotic exposure. Having this in mind and considering the ecological relevance of diatom fatty acid profiles as well as...
Untargeted metabolomics reveals antidepressant effects in a marine photosynthet...
Duarte, Bernardo; Feijão, Eduardo; Cruz de Carvalho, Ricardo; Duarte, Irina A.; Marques, Ana Patrícia; Maia, Marisa; Hertzog, Jasmine; Matos, Ana RitaThe increased use of antidepressants, along with their increased occurrence in aquatic environments, is of concern for marine organisms. Although these pharmaceutical compounds have been shown to negatively affect marine diatoms, their mode of action in these non-target, single-cell phototrophic organisms is yet unknown. Using a Fourier-transform ion cyclotron-resonance mass spectrometer (FT-ICR-MS) we evaluate...
Fluoxetine induces photochemistry-derived oxidative stress on Ulva lactuca
Feijão, Eduardo; Cruz De Carvalho, Ricardo; Duarte, Irina A.; Matos, Ana Rita; Cabrita, Maria Teresa; Utkin, Andrei B.; Caçador, IsabelEmerging pollutants impose a high degree of stress on marine ecosystems, compromising valuable resources, the planet and human health. Pharmaceutical residues often reach marine ecosystems, and their input is directly related to human activities. Fluoxetine is an antidepressant, and one of the most prescribed selective serotonin reuptake inhibitors globally and has been detected in aquatic ecosystems in concent...
Fluoxetine induces photochemistry-derived oxidative stress on Ulva lactuca
Feijão, Eduardo; Cruz de Carvalho, Ricardo; Duarte, Irina A.; Matos, Ana Rita; Cabrita, Maria Teresa; Utkin, Andrei B.; Caçador, IsabelEmerging pollutants impose a high degree of stress on marine ecosystems, compromising valuable resources, the planet and human health. Pharmaceutical residues often reach marine ecosystems, and their input is directly related to human activities. Fluoxetine is an antidepressant, and one of the most prescribed selective serotonin reuptake inhibitors globally and has been detected in aquatic ecosystems in concent...
Fluoxetine Arrests Growth of the Model Diatom Phaeodactylum tricornutum by Incr...
Feijão, Eduardo; Cruz de Carvalho, Ricardo; Duarte, Irina A.; Matos, Ana Rita; Cabrita, Maria Teresa; Novais, Sara C.; Lemos, Marco F. L.Pharmaceutical residues impose a new and emerging threat to aquatic environments and its biota. One of the most commonly prescribed pharmaceuticals is the antidepressant fluoxetine, a selective serotonin re-uptake inhibitor that has been frequently detected, in concentrations up to 40 μg L-1, in aquatic ecosystems. The present study aims to investigate the ecotoxicity of fluoxetine at environmentally relevant c...
Effects of propranolol on growth, lipids and energy metabolism and oxidative st...
Duarte, Bernardo; Feijão, Eduardo; Carvalho, Ricardo Cruz de; Duarte, Irina A.; Silva, Marisa; Matos, Ana Rita; Cabrita, Maria Teresa; Novais, Sara C.Present demographic trends suggest a rise in the contributions of human pharmaceuticals into coastal ecosystems, underpinning an increasing demand to evaluate the ecotoxicological effects and implications of drug residues in marine risk assessments. Propranolol, a non-selective B-adrenoceptor blocker, is used worldwide to treat high blood pressure conditions and other related cardiovascular conditions. Although...
Comfortably numb: Ecotoxicity of the non-steroidal anti-inflammatory drug ibupr...
Feijão, Eduardo; Carvalho, Ricardo da Cruz de; Duarte, Irina A.; Matos, Ana Rita; Cabrita, Maria Teresa; Barreiro, Aldo; Lemos, Marco F.L.Emerging pollutants such as pharmaceuticals are continuously released to aquatic environments posing a rising threat to marine ecosystems. Yet, monitoring routines and ecotoxicity data on biota worldwide for these substances are lacking. Non-steroidal anti-inflammatory drugs are among the most prescribed and found pharmaceuticals in aquatic environments. The toxicity effects of environmentally relevant concentr...