64 documents found, page 1 of 7
The Impact of a Western Diet and Resistance Training in a Rat Model of Mammary ...
Silva, Jessica; Ferreira, Rita; Neuparth, Maria J.; Seixas, Fernanda; Ginja, Mário; Pires, Maria J.; Faustino-Rocha, Ana I.; Duarte, José AlbertoThis study aimed to investigate the impact of a Western diet and resistance training on cardiac remodeling in a rat model of chemically induced mammary cancer. Fifty-six female Wistar rats were randomly assigned to one of eight experimental groups, evaluating the impact of Western and standard diets, exercise and sedentarism, and the induction of mammary cancer. Mammary cancer was induced via the intraperitonea...
Interplay Between Western Diet and Mammary Cancer: Data from a Chemically-induc...
Silva, Jessica; Aires, Inês; Peixoto, Francisco P.; Neuparth, Maria João; Queiroga, Felisbina; Seixas, Fernanda; Ferreira, Rita; Faustino-Rocha, AnaThis study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N-nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), and standard diet ...
Realistic Aspects of Cardiac Ultrasound in Rats: Practical Tips for Improved Ex...
Silva, Jessica; Ginja, Mário; Oliveira, Paula A.; Duarte, José Alberto; Faustino-Rocha, AnaEchocardiography is a reliable and non-invasive method for assessing cardiac structure and function in both clinical and experimental settings, offering valuable insights into disease progression and treatment efficacy. The successful application of echocardiography in murine models of disease has enabled the evaluation of disease severity, drug testing, and continuous monitoring of cardiac function in these an...
Physical activity, strength training and nutritional support in patients with m...
Bragada, José A.; Teixeira, José Eduardo; Bragada, João P.; Duarte, José Alberto; Pontes, João H.; Saldanha, Laissa de Sousa; Magalhães, PedroMetabolic syndrome (MetS) is a common metabolic disorder characterized by a cluster of factors such as central obesity, dysglycemia, dyslipidaemia and hypertension (1). The combination of these factors increases the risk of metabolic and cardiovascular diseases. The prevalence of MetS has been increasing in the Portuguese population (2). Primary prevention using physical activity (PA), exercise and healthy life...
Lifelong exercise training promotes the remodelling of the immune system and pr...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Palmeira, Carlos; Martins, Gabriela; Fonseca, Carolina; Duarte, José Alberto; Faustino-Rocha, Ana IThis work aimed to understand how lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of PCa. Fifty-five male Wistar rats were divided into four groups: control sedentary, control exercised, induced PCa sedentary and induced PCa exercised. Exercised animals were trained in a treadmill for 53 weeks. Pca induction consisted on the sequential administratio...
EMG signal processing for the study of localized muscle fatigue—pilot study to ...
Rodrigues, Sandra Beatriz; Faria, Luís Palermo; Monteiro, A.M.; Lima, José; Barbosa, Tiago M.; Duarte, José AlbertoThis pilot study aimed to explore a method for characterization of the electromyogram frequency spectrum during a sustained exertion task, performed by the upper limb. Methods: Nine participants underwent an isometric localized muscle fatigue protocol on an isokinetic dynamometer until exhaustion, while monitored with surface electromyography (sEMG) of the shoulder’s external rotators. Firstly, three methods of...
Exercise training in the spectrum of breast cancer
Figueira, Ana; Pereira, A; Leitão, Luís; Ferreira, Rita; Duarte, José AlbertoExercise training and regular physical activity have been mentioned as one of the non-pharmacological approaches to enhance breast cancer outcomes. Such evidence encourages health professionals to recommend it as an adjuvant in treatment conditions to improve cardiorespiratory fitness that, can increase the rate of completion of pharmacologic therapies, reduce cancer-related fatigue, and improve muscle strength...
Effects of physical exercise in biochemical parameters and dorsolateral prostat...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria João; Moreira-Gonçalves, DanielBackground: Prostate cancer (PCa) is among the most prevalent cancers worldwide. Physical exercise is widely recognized due to its beneficial effects. This study aimed to evaluate the effects of physical exercise on biochemical pa- rameters and in dorsolateral prostate lesions in a rat model of PCa. Materials and Methods: Ninety-five male Wistar Unilever rats were randomly divided into eight groups sacrificed a...
Effects of physical exercise in biochemical parameters and dorsolateral prostat...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria João; Moreira-Gonçalves, DanielProstate cancer (PCa) is among the most prevalent cancers worldwide. Physical exercise is widely recognized due to its beneficial effects. This study aimed to evaluate the effects of physical exercise on biochemical parameters and in dorsolateral prostate lesions in a rat model of PCa. Ninety-five male Wistar Unilever rats were randomly divided into eight groups sacrificed at 35 (groups I) or 61 weeks of age (g...
Exercise training as a potential therapeutic agent for prostate neoplasia in a ...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Lemos, Sílvia; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria JoãoIntroduction: Exercise training is widely recognized for its beneficial health outcomes, namely in prostate cancer (PCa). This study aimed to evaluate the effect of exercise training on dorsolateral prostate lobe lesions in a rat model of chemically and hormonally induced prostate cancer. Material & methods: Fifty-five male Wistar Unilever rats (Rattus norvegicus) of 12 weeks of age were randomly divided into f...