12 documents found, page 1 of 2
Novel knee implant fixation technology: 3D printed foamed bioactive screw/elect...
Rodrigues, Mafalda; Moreira, Rui; Silva, Inês V.; Duarte, Marta M.; Ribeiro, Viviana P.; Oliveira, Ana L.; Costa, João B.Introduction: Musculoskeletal injuries, widespread across all ages, genders, and sociodemographic groups1, are prevalent in the knee joint. Besides the conservative treatments and physiotherapy, several degenerative and traumatic knee injuries require surgical intervention2. To address one of the most significant challenges in surgical orthopaedic procedures, long-term implant fixation3, an innovative solution ...
Hydrogel-forming potential of sulphated exopolysaccharide (EPS) from Porphyridi...
Duarte, Marta M.; Suprinovych, Artem; Veiga, Anabela; Silva, Inês V.; Morais, R. M.; Oliveira, Ana L.Introduction: Gel-like materials have been on the forefront of biomedical research due to their properties such as easily adaptable shape, water-holding ability, and their adjustable degrading rate. Hydrogels from natural origin are gaining attention both for its growing popularity as “green” materials, and due to their many useful properties as compared to synthetic ones, as they are often biocompatible, and b...
Porphyridium cruentum: a factory for the production of a new polysaccharide-bas...
Duarte, Marta M.; Suprinovych, Artem; Silva, Inês V.; Ramos, Oscar L.; Costa, Joana R.; Rojo, Luis; Oliveira, Ana L.Marine algae and their metabolites have been widely recognized for their bioactive properties with applications in various industries, such as nutraceutical, cosmetical, and pharmaceutical. In this study, the best strategy for the extraction and processing of the exopolysaccharides (EPS) from Poryphydium cruentum for a laboratory scale was discussed, and the collected, purified EPS fraction was extensively char...
3D printed bioactive interference screw and PCL bio-filler for ligament fixation
Rodrigues, Mafalda; Moreira, Rui; Silva, Inês V.; Duarte, Marta M.; Ribeiro, Viviana P.; Oliveira, Ana L.; Costa, João B.Musculoskeletal injuries, widespread across all ages, genders and sociodemographic groups, are prevalent in the knee joint and require a range of treatments - from conservative methods to surgical interventions, such as meniscal resection, repair, reconstruction or tissue engineering (TE) approaches. To address one of the most significant challenges in orthopedic procedures – long-term implant fixation – an inn...
Insights on the hydrogel-forming ability of exopolysaccharide (EPS) from porphy...
Duarte, Marta M.; Suprinovych, Artem; Veiga, Anabela; Silva, Inês V.; Oliveira, Ana L.Marine algae and their metabolites have been widely recognized for their bioactive properties with applications in various industries, such as nutraceutical, cosmetical, and pharmaceutical. In this work the extracted sulfated exopolysaccharides (EPS) from Porphyridium cruentum were analyzed for their hydrogel-forming ability and potential to be used as a new platform for healing and regeneration of chronic woun...
Continuous production of highly tuned silk/calcium-based composites: exploring ...
Veiga, Anabela; Magalhães, Rui; Duarte, Marta M.; Dias, Juliana R.; Alves, Nuno M.; Costa-Pinto, Ana Rita; Castro, Filipa; Rocha, FernandoCalcium plays an important role in barrier function repair and skin homeostasis. In particular, calcium phosphates (CaPs) are well established materials for biomedical engineering due to their biocompatibility. To generate biomaterials with a more complete set of biological properties, previously discarded silk sericin (SS) has been recovered and used as a template to grow CaPs. Crucial characteristics for skin...
Continuous production of highly tuned silk/calcium-based composites: exploring ...
Veiga, Anabela; Magalhaes, Rui; Duarte, Marta M.; Dias, Juliana R.; Alves, Nuno M.; Costa-Pinto, Ana Rita; Castro, Filipa; Rocha, FernandoCalcium plays an important role in barrier function repair and skin homeostasis. In particular, calcium phosphates (CaPs) are well established materials for biomedical engineering due to their biocompatibility. To generate biomaterials with a more complete set of biological properties, previously discarded silk sericin (SS) has been recovered and used as a template to grow CaPs. Crucial characteristics for skin...
Current trends on protein driven bioinks for 3D printing
Veiga, Anabela; Silva, Inês V.; Duarte, Marta M.; Oliveira, Ana L.In the last decade, three-dimensional (3D) extrusion bioprinting has been on the top trend for innovative technologies in the field of biomedical engineering. In particular, protein-based bioinks such as collagen, gelatin, silk fibroin, elastic, fibrin and protein complexes based on decellularized extracellular matrix (dECM) are receiving increasing attention. This current interest is the result of protein’s tu...
Fast decellularization process using supercritical carbon dioxide for trabecula...
Duarte, Marta M.; Ribeiro, Nilza; Silva, Inês V.; Dias, Juliana R.; Alves, Nuno M.; Oliveira, Ana L.Decellularization is a process that consists on the removal of immunogenic cellular material from a tissue, so that it can be safely implanted as a functional and bioactive scaffold. Most decellularization protocols rely on the use of harsh chemicals and very long washing processes, leading to severe changes in the ultrastructure and loss of mechanical integrity. To tackle these challenges, supercritical carbon...
Fast decellularization process using supercritical carbon dioxide for trabecula...
Duarte, Marta M.; Ribeiro, Nilza; Silva, Inês V.; Dias, Juliana R.; Alves, Nuno M.; Oliveira, Ana L.Decellularization is a process that consists on the removal of immunogenic cellular material from a tissue, so that it can be safely implanted as a functional and bioactive scaffold. Most decellularization protocols rely on the use of harsh chemicals and very long washing processes, leading to severe changes in the ultrastructure and loss of mechanical integrity. To tackle these challenges, supercritical carbon...