3 documents found, page 1 of 1
Comprehensive multi-omics database for highly infectious viruses: a focus on HI...
Lima, A. S.; Carneiro, J.; Sousa, S.; Sá, Vítor Júlio; Pratas, D.Highly infectious viruses, such as HIV, Ebola, and SARS-CoV-2, continue to pose significant threats to global health, underlining the urgent need for new therapeutic approaches. Recent advancements in genomic and proteomic databases, along with 3D homology modelling, have enabled detailed simulations of virus-host interactions, providing insights into infection mechanisms and helping identify potential therapeu...
A multi-omics and primer database for virus identification: Focus on HIV, Ebola...
Lima, A. S.; Carneiro, J.; Sousa, S.; Sá, Vítor Júlio; Pratas, D.; Sá, Vítor J.Highly infectious viruses such as HIV, Ebola, and SARS-CoV-2 have presented ongoing challenges to global health. Consequently, the optimization of rapid detection tests, including PCR, and the identification of new therapeutic targets remain of paramount importance. The development of genomic and proteomic databases like the HIV Oligonucleotide Database (HIVoligoDB), EbolaID, and CoV2ID has facilitated the accu...
XS: a FASTQ read simulator
Pratas, D.; Pinho, A .J.; Rodrigues, J. M.The emerging next-generation sequencing (NGS) is bringing, besides the natural huge amounts of data, an avalanche of new specialized tools (for analysis, compression, alignment, among others) and large public and private network infrastructures. Therefore, a direct necessity of specific simulation tools for testing and benchmarking is rising, such as a flexible and portable FASTQ read simulator, without the nee...