28 documents found, page 1 of 3
Pregnancy and pregnancy outcomes in women with eating disorders: a four-year lo...
Machado, Bárbara César; Gonçalves, Sónia; Duarte, Sofia; Brandão, Isabel; Roma-Torres, António; Soares, FilipaBackground/Objectives: Eating disorders (EDs) often affect fertility, yet many women with ED still become mothers. The pattern of ED symptoms during pregnancy and postpartum, along with their effects on maternal and child health, is not yet fully understood. This longitudinal study aimed to (1) examine the course of ED symptoms from conception to postpartum, (2) evaluate pregnancy outcomes and children’s health...
Multi-marker DNA metabarcoding for precise species identification in ichthyopla...
Ferreira, André O.; Barroso, Cristina; Azevedo, Olga Mouteira; Duarte, Sofia; Egas, Conceição; Fontes, João T.; Ré, Pedro; Santos, A. Miguel P.Ichthyoplankton monitoring is crucial for stock assessments, offering insights into spawning grounds, stock size, seasons, recruitment, and changes in regional ichthyofauna. This study evaluates the efficiency of multi-marker DNA metabarcoding using mitochondrial cytochrome c oxidase subunit I (COI), 12S rRNA and 16S rRNA gene markers, in comparison to morphology-based methods for fish species identification in...
Mycotoxins in Rice Correlate with Other Contaminants? A Pilot Study of the Port...
Silva, Liliana; Pereira, André; Duarte, Sofia; Pedro, Inês; Perdigão, Catarina; Silva, Alexandra; Lino, Celeste M.; Almeida, Anabela; Pena, AngelinaRice is the second most important cereal crop and is vital for the diet of billions of people. However, its consumption can increase human exposure to chemical contaminants, namely mycotoxins and metalloids. Our goal was to evaluate the occurrence and human exposure of aflatoxin B1 (AFB1), ochratoxin A (OTA), zearalenone (ZEN), and inorganic arsenic (InAs) in 36 rice samples produced and commercialized in Portu...
Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies
Kumar, Mahesh; Virmani, Tarun; Kumar, Girish; Deshmukh, Rohitas; Sharma, Ashwani; Duarte, Sofia; Brandão, Pedro; Fonte, PedroThe World Health Organization identifies tuberculosis (TB), caused by Mycobacterium tuberculosis, as a leading infectious killer. Although conventional treatments for TB exist, they come with challenges such as a heavy pill regimen, prolonged treatment duration, and a strict schedule, leading to multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. The rise of MDR strains endangers future TB c...
Nanocarriers in Tuberculosis treatment: Challenges and delivery strategies
Kumar, Mahesh; Virmani, Tarun; Kumar, Girish; Deshmukh, Rohitas; Sharma, Ashwani; Duarte, Sofia; Brandão, Pedro; Fonte, PedroThe World Health Organization identifies tuberculosis (TB), caused by Mycobacterium tuberculosis, as a leading infectious killer. Although conventional treatments for TB exist, they come with challenges such as a heavy pill regimen, prolonged treatment duration, and a strict schedule, leading to multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains. The rise of MDR strains endangers future TB c...
Mycotoxins Exposure in Cabinda, Angola-A Pilot Biomonitoring Survey of Breastmilk
Duarte, Sofia; Silva, Liliana J. G.; Pereira, André; Gimbi, Marta; Cesar, Cristiane; Vidal, Vanessa; Basílio, Rita; Almeida, Anabela; Lino, CelesteBreast milk is considered the ideal form of nutrition for newborns and infants. However, it can carry over contaminants, namely mycotoxins, with biological effects to which this population is particularly vulnerable. Human biomonitoring and surveillance programs are particularly scarce in low-income countries, where food security is a more urgent priority in comparison with food safety. This pilot survey aims t...
Generation and characterization of induced pluripotent stem cell line (IBBISTi0...
Maranga, Carina; Pereira, Carolina; Raposo, Ana Cláudia; Vieira, Adriana A.; Duarte, Sofia; Bekman, Evguenia; Milagre, Inês; da Rocha, Simão T.Angelman Syndrome is a rare neurodevelopmental disorder caused by several (epi)genetic alterations. The patients present strong neurological impairment due to the absence of a functional maternal UBE3A gene in neurons. Here, we generated and characterized a new induced pluripotent stem cell (iPSC) line from a female child with Angelman syndrome harbouring a class II deletion. iPSCs were reprogrammed from fibrob...
Association between IL-1A, IL-1B and IL-1RN polymorphisms and peri-implantitis ...
Cardoso, José Maria; Duarte, Sofia; Ribeiro, Ana Clara; Mascarenhas, Paulo; Noronha, Susana; Alves, Ricardo CastroRecent studies report that individuals with polymorphisms in the genes that encode for interleukin (IL)-1α and IL-1β (IL-1A and IL1B, respectively) and for IL-1 receptor antagonist (IL-1RN) may be more susceptible in developing peri-implantitis. Therefore, the current systematic review evaluates what is reported about the role of genetics, more specifically of single nucleotide polymorphisms (SNP) on IL-1 and v...
Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part I-Lessons...
Pena, Angelina; Duarte, Sofia; Pereira, André M. P. T.; Silva, Liliana J. G.; Laranjeiro, Célia S. M.; Oliveira, Marta; Lino, Celeste; Morais, SimoneHuman biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by determining the parent compounds, their metabolites or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are disperse and...
Human Biomonitoring of Selected Hazardous Compounds in Portugal: Part II-Lesson...
Pena, Angelina; Duarte, Sofia; Pereira, André; Silva, Liliana J. G.; Laranjeiro, Célia S. M.; Oliveira, Marta; Lino, Celeste; Morais, SimoneHuman biomonitoring (HBM) data provide information on total exposure regardless of the route and sources of exposure. HBM studies have been applied to quantify human exposure to contaminants and environmental/occupational pollutants by means of determining the parent compounds, their metabolites, or even their reaction products in biological matrices. HBM studies performed among the Portuguese population are di...