A central composite design circumscribed method was used to define the experimental conditions that improve the methane production rate (kCH4, liters of methane per kilogram of VS of waste added and per day) and the cumulative methane production (cMP, liters of methane per kilogram of VS of waste added) of the co-digestion of sewage sludge (SS) with crude glycerol (cGly) and waste frying oil (WFO). Three factor...
Redirection of sewage sludge in wastewater treatment plants (WWTP) from landfilling or incineration to biological treatment, for instance anaerobic digestion, has become a part of the current global environmental, economic and regulatory issues. A statistical approach, based on a design of experiments, was adopted in order to assess methane production from the anaerobic co-digestion of mixed sewage sludge (MS) ...
In hereditary hemochromatosis, iron deposition in the liver parenchyma may lead to fibrosis, cirrhosis and hepatocellular carcinoma. Most cases are ascribed to a common mutation in the HFE gene, but the extent of clinical expression is greatly influenced by the combined action of yet unidentified genetic and/or environmental modifying factors. In mice, transcription factor NRF2 is a critical determinant of hepa...
Hepcidin regulates systemic iron homeostasis. Suppression of hepcidin expression occurs physiologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemochromatosis. Here we show that epigenetic events govern hepcidin expression. Erythropoiesis and iron deficiency suppress hepcidin via erythroferrone-dependent and -independent mechanisms, respectively, in vivo, but both i...
4º Congresso de Argamassas de Construção da APFAC. Coimbra, U.Coimbra, APFAC/ITeCons, 29-30 Março 2012; Com o intuito de explorar a viabilidade da integração de resíduos da indústria cerâmica em argamassas de cal aérea destinadas à reabilitação de rebocos antigos, foram caracterizadas argamassas com três tipos de resíduos na sua composição: provenientes de telhas, de tijolos e de vasos. A incorporação dos resíd...