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HLA-G genetic diversity and evolutive aspects in worldwide populations

Castelli, Erick C. [UNESP]; de Almeida, Bibiana S.; Muniz, Yara C. N.; Silva, Nayane S. B. [UNESP]; Passos, Marília R. S. [UNESP]

Made available in DSpace on 2022-04-29T08:46:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HLA-G genetic variability in 4640 individuals from 88 di...

Date: 2022   |   Origin: Oasisbr

Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Br...

Naslavsky, Michel S.; Scliar, Marilia O.; Yamamoto, Guilherme L.; Wang, Jaqueline Yu Ting; Zverinova, Stepanka; Karp, Tatiana; Nunes, Kelly

Made available in DSpace on 2022-04-29T08:46:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-12-01; National Institute of General Medical Sciences; As whole-genome sequencing (WGS) becomes the gold standard tool for studying population genomics and medical applications, data on diverse non-European and admixed individuals are still scarce. Here, we present a high-coverage WGS dataset of 1,171 highly a...

Date: 2022   |   Origin: Oasisbr

Methodological Description of Mapping Brazilian Long-Term Care Facilities for O...

Domingues, Marisa Accioly Rodrigues da Costa; Wachholz, Patrick Alexander; Silva, Christiano Barbosa da; Peres, Lidiane Charbel Souza

Aim: describe the methodological approach adopted to build a Brazilian database of LCTFs in the country. Methods: This exploratory research was conducted between August 2020 and 2021 based on primarily publicly accessible data. First, the database of the Sistema Único de Assistência Social for 2019 was adopted as the primary source of information. In addition, public agencies and managers were consulted and inv...

Date: 2021   |   Origin: Oasisbr

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