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New 1-hydroxy-1,1-bisphosphonates derived from 1H-pyrazolo[3,4-b]pyridine: synt...
Teixeira,Fátima C.; Lucas,Carla; Curto,M. João M.; Neves,M.; Duarte,M. Teresa; André,Vânia; Teixeira,António P. S.A number of 1H-pyrazolo[3,4-b]pyridine derivatives, starting from 2-chloro-3-formyl pyridine, was synthesized to obtain new 1-hydroxybisphosphonates, a class of compounds with potential biological interest. Spectroscopic data were used to characterize all compounds and to identify N-1 and N-2 regioisomers, and mono-and bisphosphonates derivatives. X-ray diffractometry studies of compound 7a confirmed the propos...
Date: 2013
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Origin: Oasisbr