RESUMO Este trabalho tem como objetivo a preparação de mantas compostas por fibras do polímero biodegradável poli(3-hidroxibutirato) -(PHB) por meio da técnica de eletrofiação. Obtiveram-se mantas sob diferentes condições, variando-se o fluxo, a temperatura da solução, a tensão aplicada e a adição de um agente surfactante. O material obtido foi analisado por microscopia eletrônica de varredura (MEV), calorimetr...
Resumo Os dispositivos de fixação óssea, metálicos convencionais, usados em cirurgia crâniomaxilofacial têm apresentado alguns problemas, tais como, corrosão, inflamação e infecção, além de neoformação de estrutura óssea mecanicamente inferior devido à atrofia gerada pela diferença de módulo elástico entre metal e osso, razões que têm levado ao aumento do interesse por dispositivos poliméricos bioarreabsorvívei...
This study aims the synthesis of copolymers of poly (l-lactic acid) and polycaprolactone by ring opening polymerization. The reactions between l-lactide (LLA) and ε-caprolactone (CL) monomers, in 100/0, 95/5, 90/10 and 80/20 LLA/CL mass ratios, were conducted in refluxing toluene, using Stannous octoate as iniciator, methanol as co-iniciator and inert atmosphere (N2). The reaction medium was maintained under st...
The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/P...
Poly (L-co-D,L lactic acid) (PLDLA) is an important biomaterial because of its biocompatibility properties that promote cellular regeneration and growth. The aim of this study was to evaluate the polymer-tissue interaction of PLDLA implants in the dorsal subcutaneous tissue of male Wistar rats at various intervals (2, 7, 15, 30, 60 and 90 days) after implantation. Physical properties such as the glass transitio...
Aiming the development of high-performance biodegradable polymer materials, the properties and the processing behavior of poly(3-hydroxybutyrate), P(3HB), and their blends with poly(epsilon-caprolactone), PCL, have been investigated. The P(3HB) sample, obtained from sugarcane, had a molecular weight of 3.0 x 10(5) g.mol¹, a crystallinity degree of 60%, a glass transition temperature (Tg), at - 0.8 °C, and a mel...