13 documents found, page 1 of 2
Upregulation of intercellular adhesion molecule-1 and vascular cell adhesion mo...
Vitoria,Webster Oliveira; Thomé,Letícia Silva; Kanashiro-Galo,Luciane; Carvalho,Leda Viegas de; Penny,Ricardo; Santos,Washington Luis ConradoAbstract INTRODUCTION: Dengue is an important mosquito-borne disease in tropical and subtropical regions. Adhesion molecules have not been systematically characterized in the renal tissue of patients with severe dengue (SD). The objective of this study was to detect viral antigens in samples from patients that evolved with SD, correlating with the expression of ICAM-1, VCAM-1, VE-cadherin, and E-selectin to con...
Basal ganglia lesions in subacute sclerosing panencephalitis
Almeida,Kelson James; Brucki,Sonia Maria Dozzi; Duarte,Maria Irma Seixas; Pasqualucci,Carlos Augusto Gonçalves; Rosemberg,Sérgio; Nitrini,RicardoABSTRACT The parieto-occipital region of the brain is the most frequently and severely affected in subacute sclerosing panencephalitis (SSPE). The basal ganglia, cerebellum and corpus callosum are less commonly involved. We describe a patient with SSPE confirmed by neuropathology based on brain magnetic resonance imaging showing extensive basal ganglia involvement and no significant involvement of other cortica...
Immune reconstitution inflammatory syndrome associated with pulmonary sarcoidos...
Miranda,Érique José Peixoto de; Leite,Olavo Henrique Munhoz; Duarte,Maria Irma SeixasSarcoidosis has been rarely described in literature as a cause of interstitial pulmonary disease associated with AIDS. This study reports a case of immune reconstitution inflammatory syndrome associated with pulmonary sarcoidosis in a patient with a history of previous pulmonary tuberculosis concomitant with HIV infection. Results of the immunohistochemical study of samples from the resected right lower lobe ar...
Cytokine expression in the duodenal mucosa of patients with visceral leishmaniasis
Luz,Kleber Giovanni; Tuon,Felipe Francisco; Duarte,Maria Irma Seixas; Maia,Guilherme Mariz; Matos,Paulo; Ramos,Ana Maria de OliveiraINTRODUCTION: Visceral leishmaniasis (VL) is a neglected tropical disease with a complex immune response in different organs. This pattern of organ-specific immune response has never been evaluated in the gastrointestinal tract. The aim of this study was to determine the in situ immune response in duodenal biopsies on patients with VL. METHODS: A case-control study was conducted on 13 patients with VL in compar...
Hepatitis C virus and human T-lymphotropic virus coinfection: epidemiological, ...
Milagres,Flávio Augusto Pádua; Duarte,Maria Irma Seixas; Viso,Ana Teresa; Segurado,Aluisio CotrimTwenty-four hepatitis C virus patients coinfected with human T-lymphotropic virus type 1 were compared with six coinfected with HTLV-2 and 55 with HCV alone, regarding clinical, epidemiological, laboratory and histopathological data. Fischer's discriminant analysis was applied to define functions capable of differentiating between the study groups (HCV, HCV/HTLV-1 and HCV/HTLV-2). The discriminant accuracy was ...
Immunohistochemical study of the cellular immune response in human Pneumocystis...
Castro,Leandro Mantovani de; Pagliari,Carla; Fernandes,Elaine Raniero; Brasil,Roosecelis Araújo; Duarte,Maria Irma SeixasOBJECTIVES: It has been experimentally demonstrated that host defense against Pneumocystis carinii depends on complex interactions within host immune response, mainly CD4 lymphocytes and alveolar macrophages. Since this is an important agent related to immunodeficiency, our purpose was to characterize the inflammatory immune response in lung from necropsy of AIDS patients. PROCEDURES: Twenty-five necropsies wit...
Eritema nodoso como forma de reativação da doença de Chagas em transplantado ca...
d'Ávila,Solange Corrêa Garcia Pires; d'Ávila,Antônio Miguel Morena Pires; Pagliari,Carla; Gonçalves,Verônica M.; Duarte,Maria Irma SeixasO presente caso ilustra uma forma de eritema nodoso, cujo agente foi o Trypanosoma cruzi em paciente chagásica submetida a transplante cardíaco. O diagnóstico foi firmado através do exame histopatológico de biópsia da lesão cutânea e estudo imunohistoquímico. O tratamento com nifurtimox promoveu regressão total das lesões.
Lesões cutâneas como únicas manifestações de reativação da infecção pelo Trypan...
Amato,Juliane Gomes de Paula; Amato Neto,Vicente; Amato,Valdir Sabbaga; Duarte,Maria Irma Seixas; Uip,David Everson; Boulos,MarcosPaciente com doença de Chagas, em fase crônica, após ter sido submetida a transplante de rim sofreu reativação da infecção devido ao Trypanosoma cruzi, como conseqüência de imunodepressão medicamentosa. O acontecimento manifestou-se exclusivamente através de lesões cutâneas ulceradas, merecendo portanto divulgação tal aspecto clínico inusitado.
Acute exacerbation in chronic hepatitis B virus infection
Santos,Marcio Vieira; Duarte,Maria Irma Seixas; Barone,Antonio AlciA case of an acute exacerbation of liver injury in a chronic HBV infected young male is reported. The correlation between the severe symptomatic hepatitis is done with the histopathologic findings of extense areas of bridging necrosis on the Iwer biopsy. The serological pattern for markers of HBV (HBsAg +, anti HBs g -, HBeAg -, anti HBe +, anti HBcIgG + and IgM -) confirm a chronic infection, ana the authors p...
Tratamento da Leishmaniose tegumentar americana, com lesão em mucosa, por meio ...
Amato,Valdir Sabbaga; Paula,Juliane Gomes de; Imamura,Rui; Amato Neto,Vicente; Duarte,Maria Irma Seixas; Boulos,Maria Ivete Castro; Boulos,MarcosDez pacientes com leishmaniose tegumentar americana, acometidos de lesão em mucosa, foram tratados por meio do isotionato de pentamidina na dose de 4mg/kg, em dias alternados, por via endovenosa. A posologia média correspondeu a 2.140mg. A cicatrização das lesões ocoireu em 9 (90%) dos pacientes que completaram o tratamento. Não houve recidiva no período de acompanhamento de 1 a 24 meses (média de 7, 7 meses). ...