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Stanozolol induces ventricular dysfunction by decreasing phospholamban phosphor...

Andrade, Tadeu Uggere de; Dubois Fillho, Dionisio; Silva, Cristiane Lyrio da; Silva, Mirian de Almeida; Almeida, Simone Alves de

Stanozolol is a steroid that causes lipid deposition in LDLr-/- mice, although the mechanism by which this dyslipidemia results in cardiac dysfunction is little understood. The aim of this study was to evaluate the effect of stanozolol on cardiac contractility and the participation of myocardial phospholamban (pPLB) phosphorylation in an atherosclerosis mouse model. LDL receptor knockout mice (LDLr-/-) were fed...

Date: 2022   |   Origin: Oasisbr
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