73 documents found, page 1 of 8
Patient organisations' views, motivations and experiences on patient involvemen...
Roquette, C.; Crisóstomo, S.; Milagre, T.; Ribeiro, R. S.; Pedro, A. R.; Valente, A.Objectives To characterise Portuguese cancer-related patient organisations and analyse their views, motivations and experiences on patient involvement in cancer research. Design A multistakeholder group, comprising patient representatives and researchers, codesigned a questionnaire after a literature review, online sessions and collaborative mind maps. In May 2021, a survey was conducted among representatives o...
Polimorfismos genéticos associados à hiperhomocisteinémia na diabetes tipo 2: c...
Bicho, M.; Valente, A.; Duarte, R.; Raposo, J.F.; Costa, H.S.Introdução: A hiperhomocisteinemia tem sido associada a polimorfismos genéticos das enzimas 5,10-metilenotetra-hidrofolato (MTHF) e cistatina-β-sintetase (CBS).
Biomarcadores cardiovasculares e da ingestão alimentar associados com a hiperte...
Valente, A.; Bicho, M.; Duarte, R.; Raposo, J.F.; Costa, H.S.INTRODUÇÃO: A diabetes é um fator de risco da hipertensão arterial. Conhecer e relacionar os níveis plasmáticos de diversos biomarcadores pode contribuir para prevenir e controlar a hipertensão arterial em diabéticos tipo 2. OBJECTIVO: Avaliar uma possível associação entre os níveis plasmáticos de biomarcadores cardiovasculares, stress oxidante e da ingestão alimentar com a hipertensão arterial em diabéticos co...
The effect of glutathione S-transferase M1 and T1 polymorphisms on ascorbic aci...
Valente, A.; Bicho, M.; Santos, A.C.; Matos, A.; Duarte, R.; Raposo, J.F.; Costa, H.S.Introduction: Type 2 diabetes mellitus have been associated with excessive production of reactive oxygen species. Glutathione S-transferase (GST) polymorphisms result in decreased or absent enzyme activity and altered oxidative stress. Meta-analyses have indicated that deletion of either GSTM1 or GSTT1 is associated with a significant increased risk of coronary heart disease. The aim of this study was to evalua...
Characterization of portuguese centenarian eating habits, nutritional biomarker...
Silva, Alda Pereira da; Valente, A.; Chaves, C.; Matos, A.; Gil, A.; Santos, A. C.; Clara, J. P. Gorjão; Bicho, M.BACKGROUND AND AIMS: Eating habits may contribute to longevity. We characterized the eating habits and cardiovascular risk (CVR) biomarkers in Portuguese centenarians (CENT) compared to controls. METHODS AND RESULTS: Centenarians (n = 253), 100.26 ± 1.98 years, were compared with 268 controls (67.51 ± 3.25), low (LCR) and high (HCR) CVR (QRISK®2-2016). Anthropometric and body composition were evaluated by bioim...
Characterization of portuguese centenarians eating habits, nutritional biomarke...
Silva, A. Pereira Silva; Valente, A.; Chaves, C.; Matos, A.; Gil, A.; Santos, A. C.; Gorjão Clara, J. P.; Bicho, M.Background and Aims: Eating habits may contribute to longevity. We characterized the eating habits and cardiovascular risk (CVR) biomarkers in Portuguese centenarians (CENT) compared to controls. Methods and results: Centenarians (n=253), 100.261.98 years, were compared with 268 controls (67.513.25), low (LCR) and high (HCR) CVR (QRISK®2-2016). Anthropometric and body composition were evaluated by bioimpedanc...
Body composition assessment and nutritional status evaluation in men and women ...
Silva, A. Pereira; Valente, A.; Matos, A.; Gorjão Clara, J. P.; Bicho, M.; Alonso, I.Objectives: To assess body composition, nutritional status and its differences between genders in a sample of Portuguese centenarians. Design: Observational cross-sectional study. Setting: Centenarians recruited in Portugal, able to give informed consent. Participants: A total of 252 subjects, with a median age of 100 years, mostly women (77.8%) who accepted to participate in the study, during the period of 201...
Biomarkers status and their relation with the presence of type 2 diabetes with ...
Valente, A.; Bicho, M.; Duarte, R.; Raposo, J.F.; Costa, H.S.Introduction: A useful tool for disease clinical characterization and treatment of type 2 diabetes is the knowledge on the status of several biomarkers. The aim of this study was to evaluate the levels of cardiovascular, oxidative stress and nutritional biomarkers and their relationship with the presence of type 2 diabetes and angiopathy. Methods: A population-based case-control study in 150 Portuguese type 2 d...
Sarcopenia and osteoporosis in Portuguese centenarians
da Silva, A. P.; Matos, A.; Ribeiro, R.; Gil, A.; Valente, A.; Bicho, M.; Clara, J. GorjãoBackground/Objectives: To evaluate the prevalence of sarcopenia and osteoporosis in centenarians and its association with body composition and past physical activity (PPA). Subjects/Methods: We conducted an observational cross-sectional study in a representative nationwide population of 253 Portuguese centenarians. A clinically oriented questionnaire and anthropometric and body composition analysis by bioimpeda...
Sumo detox e os seus ingredientes: análise comparativa da atividade antioxidant...
Santos, I.C.; Silva, M.A.; Costa, H.S.; Valente, A.; Albuquerque, T.G.Os antioxidantes e os compostos bioativos naturalmente presentes nas frutas e vegetais têm suscitado um especial interesse entre os consumidores devido aos potenciais benefícios que apresentam para a saúde. Hoje em dia, uma das formas de consumo de frutas e vegetais é sob forma de sumos detox. No entanto, é fundamental avaliar as propriedades nutricionais e bioativas dos alimentos quando se misturam, dado que g...