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Genetic profiling of Trypanosoma cruzi directly in infected tissues using neste...

Pimenta, Juliana Ramos; Freitas, Jorge Marcelo de; Duffy, Tomás; Bartholomeu, Daniella Castanheira; Oliveira, Riva de Paula; Chiari, Egler

The investigation of the importance of the genetics of Trypanosoma cruzi in determining the clinical course of Chagas disease will depend on precise characterisation of the parasites present in the tissue lesions. This can be adequately accomplished by the use of hypervariable nuclear markers such as microsatellites. However the unilocal nature of these loci and the scarcity of parasites in chronic lesions make...

Date: 2015   |   Origin: Oasisbr
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