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Circulating Tumor DNA Tracking Through Driver Mutations as a Liquid Biopsy-Base...

Bustamante, P; Tsering, T; Coblentz, J; Mastromonaco, C; Abdouh, M; Fonseca, C; Proença, RP; Blanchard, N; Dugé, CL; Andujar, RAS; Youhnovska, E

Background: Uveal melanoma (UM) is the most common intraocular tumor in adults. Despite good primary tumor control, up to 50% of patients develop metastasis, which is lethal. UM often presents asymptomatically and is usually diagnosed by clinical examination and imaging, making it one of the few cancer types diagnosed without a biopsy. Hence, alternative diagnostic tools are needed. Circulating tumor DNA (ctDNA...

Date: 2021   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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