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Methacrylated epigallocatechin gallate functionalized dental adhesives: antipro...

Duque, Cristiane; Chrisostomo, Daniela Alvim; Scaffa, Polliana Mendes Candia; Gouveia, Zach; Nascimento, Fabio Dupart; Plotnikov, Sergey V.

Objectives: To assess the antiproteolytic effect of EGCG-methacrylate monomers and its inhibitory effect on gelatinolytic activity in the hybrid layer. Also, to investigate the effect of an adhesive material functionalized with EGCG-methacrylate monomers on immediate and long-term dentin-resin bond strength. Methods: Neat EGCG (E0) was reacted with three different ratios of methacryloyl ester and dissolved in e...


Phenolic acids-loaded thermosensitive hydrogel for intracanal biofilm management

Santos, Vanessa Rodrigues dos; Caiaffa, Karina Sampaio; Souza, Amanda Caselato Andolfato; Pereira, Jesse Augusto; Abuna, Gabriel Flores

Objective: In search of an inter-appointment intracanal medication capable of promoting root canal disinfection while preserving the viability of periapical cells, this study synthesized and characterized chitosan-poloxamer hydrogels (CPH) containing phenolic acids and evaluated their effects on multispecies biofilms and cell viability for potential endodontic use. Methods: Cinnamic acid (CI), caffeic acid (CA)...


Exploring salivary biomarkers in pediatric obesity: a scoping review

Sabella, Fernanda Maria; Katzenelson, Renata Thomaz; Carvalho, Fabíola Galbiatti de; Duque, Cristiane; Darrieux, Michelle; Marson, Fernando Augusto Lima

Childhood obesity and overweight are linked to subclinical inflammatory conditions. The present manuscript aimed to undertake a scoping review exploring the relationship between childhood obesity and salivary biomarkers to answer the following question: “Are salivary biomarkers trustful factors/indicators for childhood obesity?” The main search terms used were: “obesity and salivary biomarkers and children” (Pu...


Root canal instrumentation of artificial primary teeth with rotary and reciproc...

Chrisostomo, Daniela Alvim; Danelon, Marcelle; Furlan, Renan Diego; Duarte, Marco Antônio Hungaro; Mello-Moura, Anna Carolina Volpi; Duque, Cristiane

This study compared the outcomes of two endodontic instrumentation protocols (rotary or reciprocating files), using artificial primary teeth and micro-computed tomography. Twenty-four artificial primary molars were equally distributed into two groups of 12, according to the type of instrumentation – rotary files (Sequence Baby NiTi Files©) or reciprocating files (X1-Blue File NiTi files©). The following paramet...


Cytotoxic and antibiofilm properties of antibiotic-loaded thermoresponsive hydr...

Duque, Cristiane; Braga, Gabriela Pacheco de Almeida; Carvalho, Juliana Machado de; Caiaffa, Karina Sampaio; Nunes, Gabriel Pereira

Dental infections can disrupt root development in immature permanent teeth, making traditional endodontic treatment challenging. Apexogenesis, a regenerative approach that promotes natural root development, offers a potential solution. However, issues related to disinfection and material biocompatibility still remain. The objective of this study was to evaluate the synergistic antimicrobial and antibiofilm prop...


EGCG and taxifolin modulate secretory activity and expression of dentinogenesis...

Duque, Cristiane; Rabelo, Rafaela Laruzo; Braga, Gabriela Pacheco de Almeida; Soares, Igor Paulino Mendes; Souza, Maria Eduarda de

Odontoblasts are cells specialized in dentin matrix deposition and the first line of defense when the dentin–pulp complex is injured by pathological processes, such as dental caries and trauma. Natural compounds, such as flavonoids, could be useful to stimulate odontoblast activity and reparative dentinogenesis in vital pulp therapies, especially in immature permanent teeth. This study evaluated the effect of f...


Morin-loaded chitosan-poloxamer hydrogel as an osteoinductive delivery system f...

Pereira, Jesse Augusto; Martin, Victor; Araújo, Rita; Grenho, Liliana; Gomes, Pedro; Marto, Joana; Fernandes, Maria Helena; Santos, Catarina

Considering the search for new biocompatible intracanal medicaments that can preserve remaining cells and stimulate bone tissue repair in the periapical region, this study aimed to synthesize and characterize the physicochemical properties of morin-loaded chitosan-poloxamer hydrogel (MCP) as well as to evaluate its osteogenic potential. Morin hydrate (M) was loaded into chitosan-poloxamer (CP) hydrogel and the ...


Short-term comparison between clinical and microbial profiles in diabetic and n...

Camargo, Gabriela Alessandra da Cruz Galhardo; Cortês, Marcelo Magalhães; Cörner, Ana Carolina Organista; Chrisostomo, Daniela Alvim; Duque, Cristiane

Aim: To compare clinical and microbial profiles in type 2 diabetic (DM) and non-diabetic (NDM) patients with chronic periodontitis after non-surgical periodontal therapy. Methods: 30 subjects with periodontitis were separated into two groups: 15 DM and 15 NDM. Blood parameters and clinical parameters were assessed. Subgingival biofilm samples were collected from periodontal pockets (PD > 5mm) and ckecked by ...

Date: 2022   |   Origin: Oasisbr

Gene expression of inflammatory immune factors and clinical parameters in diabe...

Camargo, Gabriela Alessandra da Cruz Galhardo; Rodrigues, Juliane Maria da Silva; Amorim, Camila Silva de; Wenderoscky, Letícia de Farias

Objective: This study evaluated clinical, glucose, and immunological parameters in patients with type 2 diabetes mellitus (DM) compared to those without systemic alterations (NDM), both with generalized chronic periodontitis. Methodology: Twenty-one patients were selected with indications of tooth loss. Surgeries were performed using the Widman flap modified to obtain a gingival collar at 1 mm from the gingival...

Date: 2022   |   Origin: Oasisbr

Analysis of Biofilm Adhesion on CAD/CAM Lithium Disilicates Under Different Typ...

Catanoze, Isabela A. [UNESP]; Souza, Heloisa S. de; Araujo, Renan C.; Limirio, Joao Pedro J. D. O.; Duque, Cristiane; Santos, Paulo H. dos

Made available in DSpace on 2022-04-28T17:21:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-16; Purpose: To evaluate the adhesion of Streptococcus mutans (S. mutans) on lithium disilicate ceramics, submitted to different intraoral polishing protocols, and the degree of surface smoothness obtained. Materials and Methods: Fifty lithium disilicate specimens were divided into 5 groups (n=10): G1-Glaze...

Date: 2022   |   Origin: Oasisbr

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