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Understanding the conformational changes and molecular structure of furoyl thio...
Cairo, Raúl Ramos; Stevens, Ana María Plutín; Oliveira, Tamires Donizeth de; Batista, Alzir Azevedo; Castellano, Eduardo Ernesto; Duque, Julio1-Acyl thioureas [R1C(O)NHC(S)NR2R3] are shown to display conformational flexibility depending on the degree of substitution at the nitrogen atom. The conformational landscape and structural features for two closely related thioureas having R1=2-furoyl have been studied. The un-substituted 2-furoyl thiourea (I) and its dimethyl analogue, i.e. 1-(2-furoyl)-3,3-dimethyl thiourea (II), have been synthesized and fu...
Date: 2018
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Origin: Oasisbr