56 documents found, page 1 of 6

Cannabis for chronic pain: mechanistic insights and therapeutic challenges

Chronic pain represents a complex and debilitating condition that affects millions of people worldwide, significantly compromising their quality of life. The conventional approach to treating this type of pain often relies on the use of opioid analgesics and anti-inflammatory drugs. While these agents are effective in the short term, they present several limitations, including the risk of dependence, severe sid...

Bioactive compounds and scavenging capacity of Adansonia digitata L. (Baobab fr...

Background: Baobab fruit is valued for its nutritional and medicinal benefits. Although it is acknowledged that baobab pulp is beneficial for health, studies that link its nutraceutical properties to the ability to eliminate reactive species (ROS and RNS) are scarce. Methods: The nutritional profile and the antioxidant properties of baobab pulp extracts from Angola were evaluated. Thus, for the first time, the ...

High-value compounds in papaya by-products (Carica papaya L. var. Formosa and A...

Background: Food waste is a global and growing problem that is gaining traction due to its environmental, ethical, social, and economic repercussions. Between 2022 and 2027, the worldwide papaya market is expected to have a huge increase, meaning a growth in organic waste, including peels and seeds. Thus, this study evaluated the potential use of peels and seeds of two mature papaya fruits as a source of bioact...

Potential of portuguese viticulture by-products as natural resources of bioacti...

Vitis vinifera is the grape variety used in the production of wine and other products. In the wine production process, many of the vine’s by-products are wasted, namely seeds and stems. Given the proportion of wine production worldwide, the quantity of by-products is beginning to be an environmental problem, making it urgent to take measures for their use to obtain bioactive compounds with health benefits. The ...

Nutraceuticals based on Portuguese grape pomaces as a potential additive in foo...

Portuguese wine industry by-products are often undervalued but constitute a potential source of bioactive phenolic compounds that can be applied as a natural additive in several industries. In this context, the present study aimed to evaluate the nutritional composition, and the phenolic profile of two Portuguese Vitis vinifera L. grape pomaces (Touriga Nacional (red variety) and Alvarinho (white variety), and ...

Invasive plants and their possible applications - phytochemical profile and bio...

Invasive species are distinguished by their simplicity in reproductive and ability to adapt to adverse environments. Biological invasion has been identified as the primary driver of global change, responsible for biotic interchange and, as a result, habitat homogenization. It is well recognized that invasive species have been one of the primary causes of native species loss in recent centuries, affecting the na...

A new approach on carotenoids: classification; bioavailability and further indu...

Carotenoids are versatile isoprenoids that have been related to a number of health benefits. Their presence in foods, dietary intake and circulating levels have been associated with a reduced incidence of obesity, diabetes, certain types of cancer, and even lower total mortality. In this review, several considerations for their safe and sustainable use in foods mostly intended for health promotion are provided....

Oxidative stress, antioxidants and biomarkers: appreciation for analytical meth...

Because of its extensive potential impact on human health, the determination of oxidative stress has been the main goal of study in several studies over the last few decades. The current work is a bibliographic review of the main methods of assessing oxidative stress in humans, taking into account the adverse effects it can do to individual quality of life and public health. To situate the theme, initially was ...

Nutraceuticals based on portuguese grape pomaces as a potential additive in foo...

Portuguese wine industry by-products are often undervalued but constitute a potential source of bioactive phenoliccompounds that can be applied as a natural additive in several industries. In this context, the present study aimed to evaluate the nutritional composition, and the phenolic profile of two Portuguese Vitis vinifera L. grape pomaces (Touriga Nacional (red variety) and Alvarinho (white variety), and t...

Biochemical changes in cardiovascular diseases