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Effect of alendronate on bone-specific alkaline phosphatase on periodontal bone...
Goes, Paula; Melo, Iracema M.; Dutra, Caio S.; Lima, Ana Patrícia S.; Lima, VilmaObjective: The study aims to evaluate the effect of alendronate (ALD) on bone-specific alkaline phosphatase (BALP) serum levels on periodontal bone loss in Wistar rats. Design: Periodontitis was induced by ligature around the upper second molar in 36 male Wistar rats ( 200 g). Groups of six animals received 0.9% saline (SAL) or ALD (0.01; 0.05; 0.25 mg kg 1, s.c.), over 11 days; then they were sacrificed and th...
Date: 2013
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Origin: Oasisbr