18 documents found, page 1 of 2
Multicomponent LBSap vaccine displays immunological and parasitological profile...
Mendonça, Ludmila Zanandreis de; Resende, Lucilene Aparecida; Lanna, Mariana Ferreira; Soares, Rodrigo Dian de Oliveira Aguiar; Roatt, Bruno MendesBackground: In past years, many researchers have sought canine visceral leishmaniasis (CVL) prevention through the characterization of Leishmania antigens as vaccine candidates. Despite these efforts, there is still no efficient vaccine for CVL control. Methods: In the present study, we performed a pre-clinical vaccine trial using BALB/c mice to compare the effects of the multicomponent LBSap vaccine with those...
Immunoregulatory profile of monocytes from cutaneous leishmaniasis patients and...
Vieira, É. L. M.; Keesen, T. S. L.; Machado, Paulo Roberto Lima; Guimarães, L. H.; Carvalho Filho, Edgar Marcelino de; Dutra, Walderez OrnelasTexto completo: acesso restrito. p. 65–72; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-03-09T12:10:51Z No. of bitstreams: 1 É. L. M. Vieira.pdf: 619772 bytes, checksum: b04d562c03f21386536a6a0d26c41f82 (MD5); Approved for entry into archive by Alda Lima da Silva (sivalda@ufba.br) on 2015-03-10T19:23:31Z (GMT) No. of bitstreams: 1 É. L. M. Vieira.pdf: 619772 bytes, checksum: b04d562c03f21386536a...
Immunoregulatory and effector activities in human cutaneous and mucosal Leishma...
Dutra, Walderez Ornelas; Faria, Daniela Rodrigues de; Machado, Paulo Roberto Lima; Guimarães, Luiz Henrique; Schriefer, Nicolaus Albert BorgesTexto completo: acesso restrito. p. 430–436; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-04-15T13:32:05Z No. of bitstreams: 1 Walderez O. Dutra.pdf: 210259 bytes, checksum: 6b92f994917e2a0c10b483f278aeb54a (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-11-04T15:21:01Z (GMT) No. of bitstreams: 1 Walderez O. Dutra.pdf: 210259 bytes, checksum: 6b92f99491...
Helminthic Infection Down-Regulates Type 1 Immune Responses in Human T Cell Lym...
Santos, Silvane Maria Braga; Rodrigues Junior, Waldyr; Muniz, André Luís Nunes; Basílio, Vanessa; Neva, Franklin A.; Dutra, Walderez OrnelasTexto completo: acesso restrito. p. 612-618.; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-11-29T11:17:26Z No. of bitstreams: 1 Silvane B. Santos.pdf: 435684 bytes, checksum: 61d491af11b14d5ca3b7008acbc433af (MD5); Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-01-07T13:33:33Z (GMT) No. of bitstreams: 1 Silvane B. Santos.pdf: 435684 bytes, checksum: 61d491af1...
Cutaneous leishmaniasis during pregnancy: exuberant lesions and potential fetal...
Morgan, Daniel J.; Guimaraes, Luiz H.; Machado, Paulo Roberto Lima; D'Oliveira Junior, Argemiro; Almeida, Roque Pacheco de; Lago, Ednaldo LimaTexto completo: acesso restrito. p. 478-482; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-21T11:51:20Z No. of bitstreams: 1 10.1086-520017.pdf: 284401 bytes, checksum: a82c59fcd9d227388c9c10c70bb4f53d (MD5); Rejected by Flávia Ferreira (flaviaccf@yahoo.com.br), reason: Por favor faça a inclusão dos autores de todos autores do artigo. Grata, on 2014-01-28T12:59:33Z (GMT); Submitted by Suelen Reis ...
Differential immune regulation of activated T cells between cutaneous and mucos...
Carvalho, Lain Carlos Pontes de; Passos, S.; Bacellar, Maria Olívia Amado Ramos; Lessa, M.; Almeida, Roque Pacheco de; Magalhães, A.Texto completo: acesso restrito. p. 251-258; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2014-01-24T15:57:07Z No. of bitstreams: 1 j.1365-3024.2007.00940.x.pdf: 240676 bytes, checksum: fcbb7c920988e7f9f6a2ee087c48d762 (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2014-09-09T16:14:33Z (GMT) No. of bitstreams: 1 j.1365-3024.2007.00940.x.pdf: 240676 bytes, checksum: fc...
Up-regulation of Th1-type responses in mucosal leishmaniasis patients
Bacellar, Olívia; Lessa, Hélio; Schriefer, Albert; Machado, Paulo Roberto Lima; Jesus, Amélia Maria Ribeiro de; Dutra, Walderez OrnelasThe cytokine profile produced by peripheral blood mononuclear cells (PBMC) in response to leishmania antigens and the ability of interleukin-10 (IL-10) and transforming growth factor β (TGF-β) to modulate the immune response were evaluated in 21 mucosal leishmaniasis patients. Patients with mucosal disease exhibited increased gamma interferon (IFN-γ) and tumor necrosis factor alpha (TNF-α) secretion and decreas...
Decreased in situ expression of interleukin-10 receptor is correlated with the ...
Faria, Daniela Rodrigues de; Gollob, Kenneth John; Barbosa Júnior, José; Schriefer, Nicolaus Albert Borges; Machado, Paulo Roberto Lima; Lessa, HélioHuman infection with Leishmania braziliensis can lead to cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML). We hypothesize that the intense tissue destruction observed in ML is a consequence of an uncontrolled exacerbated inflammatory immune response, with cytotoxic activity. For the first time, this work identifies the cellular sources of inflammatory and antiinflammatory cytokines, the expression of ...
Low levels of vasoactive intestinal peptide are associated with Chagas disease ...
Corrêa, Marielle Valério; Rocha, Manoel Otávio da Costa; Sousa, Giovane Rodrigo de; Nunes, Maria do Carmo Pereira; Gollob, Kenneth JohnThe interconnection between immune and neuroendocrine systems influences regulation of inflammatory responses. The possible relevance that this integrative response may have during the course of Chagas disease remains poorly characterized. In this context, our study was designed to determine the expression of vasoactive intestinal peptide (VIP), a neuropeptide with anti-inflammatory properties, in blood from th...
Mucosal Leishmaniasis Patients Display an Activated Inflammatory T-cell Phenoty...
Gaze, S. T.; Dutra, Walderez Ornelas; Lessa, M.; Lessa, Hélio Andrade; Guimarães, L. H.; Jesus, A. R. de; Carvalho, Lain Carlos Pontes deTexto completo: acesso restrito. p. 70–78; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-09-05T15:33:10Z No. of bitstreams: 1 j.1365-3083.2005.01707.x.pdf: 413974 bytes, checksum: 40f335d0f7b10419ad0cd38fc6a9e31f (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-14T20:06:20Z (GMT) No. of bitstreams: 1 j.1365-3083.2005.01707.x.pdf: 413974 bytes, checksum: ...