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Impact of environmental caffeine contamination in zebrafish: ecotoxicological a...

Pinto, I.; Diogo, B. S.; Antunes, S. C.; Rodrigues, S.

Background: Caffeine (CAF) is considered a suitable indicator of anthropogenic contamination of aquatic environments, and several pharmacological and biological effects have been observed in target and non-target organisms [1,2]. Objective: Assess the chronic effects of environmental concentrations of CAF in several biomarker responses in Danio rerio. Methods: After chronic exposure to CAF (0.16, 0.42, 1.09, 2....

Date: 2023   |   Origin: Scientific Letters

Study of metal presence in the sediments of three different water bodies from t...

Torre, R.; Pinto, I.; Lage, O. M.; Noyer, M.; Almeida, E.; Cravo-Laureau, C.; Duran, R.; Antunes, S. C.; Catita, J.

Background: Human impact on the planet’s biomes has been rapidly increasing over the last decades [1]. In aquatic ecosystems, an active monitoring of the water and the sediments quality is already essential to assure its suitability for human use as well as to guarantee the health of the ecosystems [2, 3]. Objectives: This work focuses on the study of metals concentration in transitional water bodies (Ave estua...

Date: 2023   |   Origin: Scientific Letters

Emerging technologies to control Brettanomyces spp. in wine: Recent advances an...

Pinto, I.; Baruzzi, F.; Cocolin, L.; Malfeito-Ferreira, Manuel

Background: The application of emerging technologies for the food preservation is a relevant topic for the industry; these technologies are highly efficient to reduce the growth of spoilage microorganisms as well as the production of undesirable microbial metabolites in foods and the processing environment. Spoilage caused by the yeast metabolic activity affects the wine marketability. These novel technologies ...


Poor disability outcomes in the management of Low Back Pain patients in Portugal

Gomes, L.A.; Cruz, Eduardo Brazete; Canhão, H.; Branco, J. C.; Rodrigues, A.; Fernandes, Rita; Caeiro, C.; Paiva, S.; Pinto, I.; Moniz, R.


Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mo...

Simão, M.; Camacho, A.; Ostertag, A.; Cohen-Solal, M.; Pinto, I.; Porto, G.; Hang Korng, E.; Cancela, M.

Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood. The main objective of this study was to investigate the role of dietary iron on osteoporosis, using as biological model the Hfe-KO mice, which have a systemic iron overload. We showed that these mice show an increased susceptibility for developing a bone l...


A importância da Comissão de Proteção Contra Radiações

Monteiro, A.; Machado, C.; Oliveira, F.; Pinto, I.

Todos os dias a nível mundial, a radiação ionizante é utilizada para geração de imagens de pacientes, em mais de 10 milhões de procedimentos de radiologia de diagnóstico. O uso crescente de radiação ionizante pode ser visto como um simples aumento do volume de trabalho ou como uma mudança no tipo de procedimentos realizados. O principal objetivo do controlo da radiação é garantir que as doses recebidas pelos pr...


Synthesis and characterization of membranes obtained by graft copolymerization ...

Santos, K. S. C. R. dos; Coelho, J. F. J.; Ferreira, P.; Pinto, I.; Lorenzetti, S. G.; Ferreira, E. I.; Higa, O. Z.; Gil, M. H.

Chitosan based membranes to be applied on wound healing as topical drug delivery systems were developed by graft copolymerization of acrylic acid (AA) and 2-hydroxyethyl methacrylate (HEMA) onto chitosan using cerium ammonium nitrate as chemical initiator. Evidence for graft copolymerization of the vinyl monomers onto chitosan was obtained by FTIR and DMTA. Swelling degree, cytotoxicity, thrombogenicity and hae...


High enthalpy and low enthalpy death in Saccharomyces cerevisiae induced by ace...

Pinto, I.; Cardoso, H.; Leão, Cecília; van Uden, N.

Acetic acid at concentrations as may occur during vinification and other alcoholic yeast fermentations induced death of glucose-grown cell populations of Saccharomyces cerevisiae IGC 4072 at temperatures at which thermal death was not detectable. The Arrhenius plots of specific death rates with various concentrations of acetic acid (0-2%, w/v) pH 3.3 were linear and could be decomposed into two distinct familie...


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