4 documents found, page 1 of 1
Gender, body mass index and rheumatoid arthritis disease activity: Results from...
Jawaheer, Damini; Olsen, Jørn; Lahiff, Maureen; Forsberg, Sinikka; Lähteenmäki, Jukka; da Silveira, Ines Guimaraes; Rocha, Francisco AirtonMade available in DSpace on 2022-04-28T18:56:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-12-01; Objective: To investigate whether body mass index (BMI), as a proxy for body fat, influences rheumatoid arthritis (RA) disease activity in a gender-specific manner. Methods: Consecutive patients with RA were enrolled from 25 countries into the QUEST-RA program between 2005 and 2008. Clinical and demogra...
Efficacy, safety, and sample quality of ultrasound‐guided synovial needle biops...
Romão, Vasco C.; Polido Pereira, Joaquim; Barros, Rita; Luis, Rita; Vidal, Bruno; Vieira De Sousa, Elsa Cristina; Vitorino, Emília; Humby, FrancesObjective: To study the efficacy, tolerability, safety, and sampling variation of ultrasound (US)-guided synovial biopsies performed in clinical practice and research. Methods: We included all patients who had a US-guided synovial needle biopsy from November 2013 to January 2018. Patients were evaluated for procedure safety and tolerability. Usefulness of synovial biopsy was considered based on contribution for...
Treatment-resistant synovitis and radiographic progression are increased in eld...
Romão, Vasco C.; Humby, Frances; Kelly, Stephen; Di Cicco, Maria; Mahto, Arti; Lazarou, Ilias; Hands, Rebecca; Rocher-Ros, VidalbaBackground: Clinical outcomes in elderly-onset rheumatoid arthritis (EORA), starting after the age of 60, are conflicting. Thus, we aimed to investigate in a unique biopsy-driven, treatment-naïve early arthritis cohort, the relationship between synovial pathobiology of elderly- (EORA) and younger-onset rheumatoid arthritis (YORA) patients through clinical, imaging and treatment response outcome-measures. Method...
Evaluation of minimally invasive, ultrasound-guided synovial biopsy techniques ...
Humby, Frances; Kelly, Stephen; Bugatti, Serena; Manzo, Antonio; Filer, Andrew; Mahto, Arti; Fonseca, João Eurico; Lauwerys, BernardObjective: Because limited data currently support the clinical utility of peripherally expressed biomarkers in guiding treatment decisions for patients with rheumatoid arthritis, the search has turned to the disease tissue. The strategic aim of the Outcome Measures in Rheumatology (OMERACT) synovitis working group over the years has been to develop novel diagnostic and prognostic synovial biomarkers. A critical...