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Integrated Expression of Circulating miR375 and miR371 to Identify Teratoma and...

Nappi, L; Thi, M; Adra, N; Hamilton, RJ; Leao, R; Lavoie, JM; Soleimani, M; Eigl, BJ; Chi, K; Gleave, M; So, A; Black, PC; Bell, R; Daneshmand, S

Active germ cell malignancies express high levels of specific circulating micro-RNAs (miRNAs), including miR-371a-3p (miR371), which is undetectable in teratoma. Teratoma markers are urgently needed for theselection of patients and treatments because of the risk of malignant transformation and growing teratoma syndrome. To assess the accuracy of plasma miR375 alone or in combination with miR371 in detecting ter...

Date: 2021   |   Origin: Saúde - CUF
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