6 documents found, page 1 of 1
Tumor Necrosis Impacts Prognosis of Patients Undergoing Resection for T1 Intrah...
Tsilimigras, DI; Ejaz, A; Cloyd, J; Guglielmi, A; Aldrighetti, L; Weiss, M; Bauer, TW; Alexandrescu, S; Poultsides, GA; Maithel, SK; Pinto Marques, HBackground: The prognostic impact of tumor necrosis among patients undergoing resection for intrahepatic cholangiocarcinoma (ICC) remains ill-defined. Methods: Patients who underwent curative-intent resection for ICC between 2000 and 2017 were identified using a multi-institutional database. The association of pathologic tumor necrosis with overall survival (OS) and recurrence-free survival (RFS) was examined. ...
The Impact of Extent of Liver Resection Among Patients with Neuroendocrine Live...
Sham, J; Ejaz, A; Gage, M; Bagante, F; Reames, B; Maithel, S; Poultsides, G; Bauer, T; Fields, R; Weiss, M; Pinto Marques, H; Aldrighetti, L; Pawlik, TBackground: Liver resection in patients with neuroendocrine liver metastasis (NELM) provides a survival benefit, yet the optimal extent of resection remains unknown. We sought to examine outcomes of patients undergoing non-anatomic (NAR) versus anatomic liver resection (AR) for NELM using a large international cohort of patients. Methods: Two hundred and fifty-eight patients who underwent curative intent liver ...
Impact of Body Mass Index on Tumor Recurrence Among Patients Undergoing Curativ...
Merath, K; Mehta, R; Hyer, JM; Bagante, F; Sahara, K; Alexandrescu, S; Pinto Marques, H; Aldrighetti, Luca; Maithel, SK; Pulitano, C; Weiss, MJBackground: The association between body mass index (BMI) and long-term outcomes of patients with ICC has not been well defined. We sought to define the presentation and oncologic outcomes of patients with ICC undergoing curative-intent resection, according to their BMI category. Methods: Patients who underwent resection of ICC were identified in a multi-institutional database. Patients were categorized as norm...
Cytoreductive Debulking Surgery Among Patients with Neuroendocrine Liver Metast...
Ejaz, A; Reames, BN; Maithel, S; Poultsides, GA; Bauer, TW; Fields, RC; Weiss, MJ; Pinto Marques, H; Aldrighetti, L; Pawlik, TMBACKGROUND: Management of neuroendocrine liver metastasis (NELM) in the setting of unresectable disease is poorly defined and the role of debulking remains controversial. The objective of the current study was to define outcomes following non-curative intent liver-directed therapy (debulking) among patients with NELM. METHODS: 612 patients were identified who underwent liver-directed therapy of NELM from a mult...
Impact of Adjuvant Chemotherapy on Survival in Patients with Intrahepatic Chola...
Reames, BN; Bagante, F; Ejaz, A; Spolverato, G; Ruzzenente, A; Weiss, M; Alexandrescu, S; Pinto Marques, H; Aldrighetti, L; Maithel, SK; Pulitano, CBACKGROUND: The benefit of adjuvant chemotherapy for resected intrahepatic cholangiocarcinoma (ICC) is unclear. The aim of the current study was to investigate the impact of adjuvant chemotherapy on survival among patients undergoing resection of ICC using a multi-institutional database. METHODS: 1154 ICC patients undergoing curative-intent hepatectomy between 1990 and 2015 were identified from 14 institutions....
The Effect of Preoperative Chemotherapy Treatment in Surgically Treated Intrahe...
Buettner, S; Koerkamp, BG; Ejaz, A; Buisman, FE; Kim, Y; Margonis, GA; Alexandrescu, S; Pinto Marques, H; Lamelas, J; Aldrighetti, L; Gamblin, TCINTRODUCTION: While preoperative chemotherapy (pCT) is utilized in many intra-abdominal cancers, the use of pCT among patients with intrahepatic cholangiocarcinoma (ICC) remains ill defined. As such, the objective of the current study was to examine the impact of pCT among patients undergoing curative-intent resection for ICC. METHODS: Patients who underwent hepatectomy for ICC were identified from a multi-inst...