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TASTY trial: protocol for a study on the triad of nutrition, intestinal microbi...

Charneca, Sofia; Hernando, Ana; Almada-Correia, Inês; Polido-Pereira, Joaquim; Vieira, Adriana; Sousa, Joana; Almeida, Ana Santos; Motta, Carla

Background: The gut microbiota has been implicated in the onset and progression of Rheumatoid Arthritis (RA). It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. This disruption allows bacterial translocation, contributing to the perpetuation of the inflammatory process. Since diet is recognised as a key environmental factor influencing...


TASTY trial: protocol for a study on the triad of nutrition, intestinal microbi...

Charneca, Sofia; Hernando, Ana; Almada-Correia, Inês; Polido Pereira, Joaquim; Vieira, Adriana; Sousa, Joana; Almeida, Ana S.; Motta, Carla Motta

Background: The gut microbiota has been implicated in the onset and progression of Rheumatoid Arthritis (RA). It has been proposed that gut dysbiosis impairs gut barrier function, leading to alterations in mucosal integrity and immunity. This disruption allows bacterial translocation, contributing to the perpetuation of the inflammatory process. Since diet is recognised as a key environmental factor influencing...


Impact of discordance between patient’s and evaluator’s global assessment on tr...

Michelsen, Brigitte; Ørnbjerg, Lykke Midtbøll; Kvien, Tore K.; Pavelka, Karel; Nissen, Michael J.; Nordström, Dan; Santos, Maria; Koca, Suleyman Serdar

Objectives: To assess the impact of 'patient's minus evaluator's global assessment of disease activity' (ΔPEG) at treatment initiation on retention and remission rates of TNF inhibitors (TNFi) in psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) patients across Europe. Methods: Real-life data from PsA and axSpA patients starting their first TNFi from 11 countries in the European Spondyloarthritis Re...


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