When people move around a town, at some point in their journey they need to cross the road using a dedicated crosswalk. However, crossing is not always done safely due to weather conditions, lack of visibility or distraction. The VALLPASS project, aims to install two lampposts in opposite positions to the direction of crossing, with various functionalities and technological innovations, creating a luminous tunn...
The energy storage batteries, employed in solar systems installed on lampposts, are usually placed in devices such as switchboards fixed at an elevation near the top of the column. However, this storage solution becomes inefficient, because it is not possible to guarantee the control of the working temperature of the batteries, due to the low thermal insulation capacity of these storage devices. In this sense, ...
Medicines are the most used health technology in Long-Term Care. The prevalence of potentially inappropriate medicines amongst Long-Term Care patients is high. Pharmacists, assisted by prescribing-assessment tools, can play an important role in optimizing medication use at this level of care. Through a modified RAND/UCLA Appropriateness Method, 13 long-term care and hospital pharmacists assessed as ‘appropriate...
The agro-food industry is responsible for the annual production of millions of tons of food waste. At the same time, consumers are more informed and conscious about their food choices, seeking convenient, healthy, and sustainable products. In response, the industry proposes to provide natural products with limited additives, while still meeting sensory, nutritional, and safety requirements. Oats (Avena sativa L...
Background: The death of a partner is a critical life event in later life, which requires grief work as well as the development of a new perspective for the future. Cognitive behavioral web-based self-help interventions for coping with prolonged grief have established their efficacy in decreasing symptoms of grief, depression, and loneliness. However, no study has tested the efficacy for reducing grief after lo...
[Except] International conservation and sustainability agendas (CBD, 2010; European Union, 2011; IPBES, 2018; United Nations, 2018) have repeatedly called for conservation, restoration and sustainable use of biodiversity as well as the enhancement of ecosystem services and benefits to society. These calls are particularly relevant for freshwater ecosystems, which combine conservation interest and high societal ...
A gestão costeira enfrenta grandes desafios relacionados com a crescente vulnerabilidade resultante do impacto de atividades antrópicas como o turismo, urbanização crescente e instalação de infraestruturas, ao que se associa um crescente risco decorrente dos impactos de alterações climáticas. Uma gestão costeira integrada requer, assim, a avaliação da vulnerabilidade e dos riscos costeiros em cenários de altera...
Purpose - The aim of this paper is to evaluate benefits, motivations, and obstacles of the implementation of ISO 22000 in the food industry and do a comparative relation in multiple countries. The study identifies the main difficulties faced by companies during the adoption process and the benefits found on their overall satisfaction with ISO 22000. Design/methodology/approach - A research was performed to iden...
Nonalcoholic fatty liver disease (NAFLD) is caused by excessive liver lipid accumulation, but insulin resistance is specifically associated with impaired lipid saturation, oxidation, and storage (esterification), besides increased de novo lipogenesis. We hypothesized that dietary glycotoxins could impair hepatic lipid metabolism in obesity contributing to lipotoxicity-driven insulin resistance and thus to the o...
Carbidopa is used for the treatment of Parkinson's disease (PD) as an inhibitor of DOPA decarboxylase, and PD patients taking carbidopa have a lower incidence of various tumors, except for breast cancer and melanoma. Recently, it was shown that carbidopa inhibits tryptophan-2,3-dioxygenase (TDO) and kynureninase enzymes. In the present study, the effect of carbidopa on the viability and metabolic profile of bre...