23 documents found, page 1 of 3

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Prognosis of Nonagenarian ICU Patients A Bayesian analysis of prospective Europ...

Dankl, Daniel; Bruno, Raphael Romano; Beil, Michael; Flaatten, Hans; Kelm, Malte; Sigal, Sviri; Szczeklik, Wojciech; Elhadi, Muhammed

Publisher Copyright: © The Author(s) 2025.; Background: As the population ages, the number of very elderly patients (≥ 90 years, nonagenarians) admitted to intensive care units (ICUs) is increasing. This trend raises concerns about the appropriateness of ICU care for this age group, especially due to the uncertainty surrounding their prognosis. Some studies suggest that elderly ICU patients have outcomes simila...


Global age-sex-specific all-cause mortality and life expectancy estimates for 2...

Schumacher, Austin E.; Zheng, Peng; Barber, Ryan M.; A, Bhoomadevi; Aalipour, Mohammad Amin; Aalruz, Hasan; Ababneh, Hazim S.; Abaraogu, Ukachukwu O.

Publisher Copyright: © 2025 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.; Comprehensive, comparable, and timely estimates of demographic metrics—including life expectancy and age-specific mortality—are essential for evaluating, understanding, and addressing trends in population health. The COVID-19 pandemic highlighted the importance of timely and all-cau...


The association of premorbid conditions with 6-month mortality in acutely admit...

de Lange, Dylan W; Soliman, Ivo W; Leaver, Susannah; Boumendil, Ariane; Haas, Lenneke E M; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech

© 2024. The Author(s).; BACKGROUND: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. METHODS: Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU betwee...


World delirium awareness and quality survey in 2023 - A worldwide point prevale...

Lindroth, Heidi; Liu, Keibun; Szalacha, Laura; Ashkenazy, Shelly; Bellelli, Giuseppe; Van Den Boogaard, Mark; Caplan, Gideon; Chung, Chi Ryang

Funding Information: H.L. is funded by the NIA 1AGK23076662-02, serves as a board member for the American Delirium Society and was the 2023 conference co-chair for the American Delirium Society, and serves as the web committee chair for the American Thoracic Society, Nursing Assembly. She has received royalties for keynote addresses at nursing conferences in 2022 and received a travel scholarship to attend the ...


Epidemiology and outcomes of hospital-acquired bloodstream infections in intens...

Tabah, Alexis; Buetti, Niccolò; Staiquly, Quentin; Ruckly, Stéphane; Akova, Murat; Aslan, Abdullah Tarik; Leone, Marc; Conway Morris, Andrew

Funding JdW is a senior clinical investigator funded by the Research Foundation Flan ders (FWO, Ref. 1881020N). ACM is supported by a Medical Research Council Clinician Scientist Fellowship (MR/ V006118/1). NB received a fellowship grant (Grant number: P4P4PM_194449) from the Swiss National Science Founda tion. Research grants were obtained from the European Society of Intensive Care Medicine (ESICM), the Europ...


In reply

Wolff, Georg; Wernly, Bernhard; Flaatten, Hans; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.


Frailty’s influence on 30-day mortality in old critically ill ICU patients

Wernly, Bernhard; Bruno, Raphael Romano; Beil, Michael; Flaatten, Hans; Kelm, Malte; Sigal, Sviri; Szczeklik, Wojciech; Elhadi, Muhammed

Funding Information: We acknowledge all members of the VIP community. Publisher Copyright: © 2023, The Author(s).; Introduction: Frailty is widely acknowledged as influencing health outcomes among critically ill old patients. Yet, the traditional understanding of its impact has predominantly been through frequentist statistics. We endeavored to explore this association using Bayesian statistics aiming to provid...


Consent is a confounding factor in a prospective observational study of critica...

Flaatten, Hans; Guidet, Bertrand; Jung, Christian; Boumendil, Ariane; Leaver, Susannah; Szczeklik, Wojciech; Artigas, Antonio; Andersen, Finn

During analysis of a prospective multinational observation study of critically ill patients ≥80 years of age, the VIP2 study, we also studied the effects of differences in country consent for study inclusion. This is a post hoc analysis where the ICUs were analyzed according to requirement for study consent. Group A: ICUs in countries with no requirement for consent at admission but with deferred consent in sur...


The global burden of cancer attributable to risk factors, 2010–19

Tran, Khanh Bao; Lang, Justin J; Compton, Kelly; Xu, Rixing; Acheson, Alistair R; Henrikson, Hannah Jacqueline; Kocarnik, Jonathan M; Penberthy, Louise

Funding: J A Loureiro reports support for the present manuscript from Scientific Employment Stimulus (FCT; CEECINST/00049/2018) as support to their salary and from UIDB/00511/2020 of the LEPABE, funded by national funds through the FCT/MCTES (PIDDAC) as research support.; BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of ef...


A retrospective cohort study comparing differences in 30-day mortality among cr...

Wernly, Bernhard; Flaatten, Hans; Beil, Michael; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.

Funding Information: The full list of members of the COVIP study group can be found in the accompanying Supplementary Table 1. Funding Open Access funding enabled and organized by Projekt DEAL. No (industry) sponsorship has been received for this investigator-initiated study.; In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day morta...


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