23 documents found, page 1 of 3
Molecular Structure Studies on Allyl Sulfonamides: Synthesis, Theoretical Treat...
Rabello,Anderson S; Rubinger,Mayura M. M; Souza,Rafael A. C; Guilardi,Silvana; Lima,Guilherme F. de; Tavares,Eder C; Zanon,Édipo P; Silva,Giovanna R. NTwo series of allyl sulfonamides, prepared from Morita-Baylis-Hillman adducts and primary aromatic sulfonamides, were fully characterized. The Z configuration for the products derived from 2-[hydroxy(phenyl)methyl]acrylonitrile (1) and E configuration for those derived from methyl 2-[hydroxy(phenyl)methyl]acrylate (2) were confirmed by X-ray diffraction for one compound of each series (1e, 2f). Density function...
New Allyldithiocarbimates: Synthesis, Structure and Antifungal Activity against...
Vidigal,Antonio E. C.; Rubinger,Mayura M. M.; Silva,Lucas F. da; Zambolim,Laércio; Pereira,Arthur B. D.; Guilardi,Silvana; Souza,Rafael A. C.Twelve tetraphenylphosphonium allyldithiocarbimates were synthesized and fully characterized by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), infrared and nuclear magnetic resonance (NMR) spectroscopies. The spectroscopic data indicated that the allyldithiocarbimate anions present Z configuration, as confirmed by X-ray crystallography. These new compounds inhibited the germination of Ph...
New Heteroleptic RuII/Diphosphine Complexes with Cytotoxicity against Human Bre...
Lima,Benedicto A. V.; Corrêa,Rodrigo S.; Graminha,Angélica E.; Varela Júnior,Jaldyr J. G.; Silva,Albérico B. F. da; Ellena,Javier; Silva,Thales E. M.The preparation, characterization, theoretical calculations and biological application of four RuII complexes with 2-picolinate (pic), 2,2’-bipyridine (bipy) and P-P as ligands [P-P = 1,1-bis(diphenylphosphino)methane (dppm-1), 1,2-bis(diphenylphosphino)ethane (dppe-2), 1,3-bis(diphenylphosphino)propane (dppp-3) or 1,1’-bis(diphenylphosphino)ferrocene (dppf-4)], is here presented. The complexes 1-4, with genera...
“Half-Sandwich”/RuII Anticancer Complexes Containing Triphenylphosphine and p-S...
Honorato,João; Oliveira,Katia M.; Leite,Celisnolia M.; Colina-Vegas,Legna; Nóbrega,Joaquim A.; Castellano,Eduardo E.; Ellena,Javier; Correa,Rodrigo S.Mononuclear and binuclear RuII/arene/triphenylphosphine complexes with p-substituted benzoic acid derivatives were prepared and characterized. These monocationic complexes of type [Ru(η6-p-cymene)(PPh3)L] (L = benzoic acid (1), p-hydroxybenzoic acid (2), p-nitrobenzoic acid (3) and terephthalic acid (4)) were characterized using various techniques, such as nuclear magnetic resonance (NMR) and matrix-assisted la...
In vitro Antiplasmodial Activities of Alkaloids Isolated from Roots of Worsleya...
Gonring-Salarini,Karla L.; Conti,Raphael; Andrade,Jean Paulo de; Borges,Bárbara Juliana P.; Aguiar,Anna Caroline C.; Souza,Juliana O. deA combined phytochemical, crystallographic and biological study of Worsleya procera roots was performed. Fifteen alkaloids were identified by gas chromatography mass spectrometry (GC-MS) and seven of them were isolated. The structures of the alkaloids were elucidated by spectroscopic methods, and a detailed crystallographic study of tazettine was carried out. The isolated alkaloids and the obtained extracts wer...
APLICAÇÃO DA ESPECTROSCOPIA RAMAN NA CARACTERIZAÇÃO DE MINERAIS PERTENCENTES A ...
Santos,Adriele R.; Menezes,Denise B.; Ellena,Javier; Andrade,Marcelo B.Lots of Educational Institutions hold their own geocollection due to its utility and versatileness in the practical formation of new generations of skillful professionals in many areas of Science and Technology. The Geoscience laboratory of the Federal University of São Carlos has a collection of minerals used in engineering, mineralogy and other technological courses ministered to undergraduates of different p...
When Serendipity Knocks on the Door: Synthesis and Physicochemical Characteriza...
Carmona-Vargas,Christian C.; Ellena,Javier; D’Vries,Richard F.; Chaur,Manuel N.Herein, we present the serendipitous obtaining of 7-chloro-2,3-dihydro-5H-thiazolo [3,2-a]pyrimidin-5-one in 40% yield by using POCl3 and a thiobarbituric acid derivative. The thiazolopyrimidine derivative was characterized by 1H nuclear magnetic resonance (NMR), UV-Vis, and Fourier transform infrared (FTIR) spectroscopy. Additionally, the structure was confirmed by single crystal X-ray diffraction, where it wa...
Facile Synthesis and Characterization of Symmetric N-[(Phenylcarbonyl) carbamot...
Silveira,Rafael G.; Catão,Anderson J. L.; Cunha,Beatriz N.; Almeida,Fernando; Correa,Rodrigo S.; Diniz,Luan F.; Tenório,Juan C.; Ellena,JavierA thiourea derivative, N-[(phenylcarbonyl)carbamothioyl]benzamide, was synthesized and characterized by elemental analysis, thermal analysis, spectroscopic methods (Fourier transform infrared (FTIR), UV-Vis, Raman, matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF), tandem mass spectrometry (MS/MS) and nuclear magnetic resonance (NMR)) and quantum-chemical calculations. The...
Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human B...
Barolli,João P.; Corrêa,Rodrigo S.; Miranda,Fabio S.; Ribeiro,Juliana U.; Bloch Jr.,Carlos; Ellena,Javier; Moreno,Virtudes; Cominetti,Márcia R.This paper describes a new series of four DNA-intercalating agents with promising anticancer activities, based on ruthenium(II) with the planar ligand dpqQX (dpqQX = dipyrido[3,2-a:2',3'-c]quinoxaline[2,3-b]quinoxaline). The complexes identified as trans-[RuCl2(dppb)(dpqQX)], cis-[RuCl2(dppb)(dpqQX)], ct-[RuCl(CO)(dppb)(dpqQX)]PF6 and ct-[RuCl2(PPh3)2(dpqQX)] (dppb = 1,4-bis(diphenylphosphine)butane and PPh3 = ...
A Potential Visible-Light NO Releaser: Synthesis, Reactivity and Vasodilator Pr...
Sousa,Aurideia P. de; Fernandes,André F.; Paz,Iury A.; Nascimento,Nilberto R. F.; Ellena,Javier; Sousa,Eduardo H. S.; Lopes,Luiz G. F.The cis-[Ru(bpy)2(4-bzpy)(NO)](PF6)3 complex was prepared (4-bzpy = 4-benzoylpyridine), and characterized by UV-visible, infrared and nuclear magnetic resonance (NMR) spectroscopies and electrochemical techniques. The reaction with cysteine was preliminarily investigated, aiming to shed light on the potential biological mechanism for NO or HNO release mediated by thiols. Furthermore, photochemical behavior of c...