4 documents found, page 1 of 1
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappa...
Ribeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Ramalho, RM; Baptista, A; Moura, MC; Camilo, ME; Rodrigues, CMPOBJECTIVES: The increasing incidence of nonalcoholic (NASH) and alcoholic steatohepatitis (ASH), associated with lack of effective treatment, has prompted intensive studies on disease pathogenesis. Apoptosis is recognized as common in liver injury and may
Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid...
Ramalho, RM; Ribeiro, PS; Sola, S; Castro, RE; Steer, CJ; Rodrigues, CMPAmyloid beta-peptide (Abeta)-induced cell death may involve activation of the E2F-1 transcription factor and other cell cycle-related proteins. In previous studies, we have shown that tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates A
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological i...
Rodrigues, CMP; Sola, S; Nan, ZH; Castro, RE; Ribeiro, PS; Low, WC; Steer, CJTauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by interrupting classic pathways of apoptosis. Intracerebral hemorrhage (ICH) is a devastating acute neurological disorder, without effective treatment, in which a significan
Association between hepatocellular apoptosis and inflammation in patients with ...
Ribeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Baptista, A; Camilo, ME; Moura, MC; Rodrigues, CMP