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Predicting children’s myopia risk: a Monte Carlo approach to compare the perfor...

Artiemjew, Piotr; Cybulski, Radosław; Emamian, Mohammad Hassan; Grzybowski, Andrzej; Jankowski, Andrzej; Lança, Carla; Mehravaran, Shiva

This study presents the initial results of the Myopia Risk Calculator (MRC) Consortium, introducing an innovative approach to predict myopia risk by using trustworthy machine-learning models. The dataset included approximately 7,945 records (eyes) from 3,989 children. We developed a myopia risk calculator and an accompanying web interface. Central to our research is the challenge of model trustworthiness, speci...


Prevalence of anisometropia and its associated factors in school-age children

Hashemi, Hassan; Khabazkhoob, Mehdi; Lança, Carla; Emamian, Mohammad Hassan; Fotouhi, Akbar

Purpose: To determine the prevalence of anisometropia and the associated demographic and biometric risk factors in children. Methods: This cross-sectional study was conducted on the elementary school children of Shahroud, east of Iran, in 2015. All rural students were recruited, while multistage cluster sampling was used to select the students in urban areas. All children underwent optometric examinations inclu...


Longitudinal changes in crystalline lens thickness and power in children aged 6...

Hashemi, Hassan; Khabazkhoob, Mehdi; Azizi, Elham; Iribarren, Rafael; Lança, Carla; Grzybowski, Andrzej; Rozema, Jos J.; Emamian, Mohammad Hassan

Objectives: To determine the three-year changes in crystalline lens power (LP) and thickness (LT) in children and their associated factors. Methods: Schoolchildren aged 6-12 years living in Shahroud, northeast Iran were examined in 2015 and 2018. The Bennett formula was used to calculate LP. Multiple generalized estimating equations (GEE) analysis was used for data analysis. Results: Among the 8089 examined eye...


Three-year change in refractive error and its risk factors: results from the Sh...

Lança, Carla; Emamian, Mohammad Hassan; Wong, Yee Ling; Hashemi, Hassan; Khabazkhoob, Mehdi; Grzybowski, Andrzej; Saw, Seang Mei; Fotouhi, Akbar

Objectives: To determine spherical equivalent (SE) progression among children in the Shahroud School Children's Eye Cohort Study. Methods: A prospective cohort study recruited children aged 6 to 12 years in 2015 (baseline) with a follow-up in 2018. Cycloplegic autorefraction and axial length (AL) measurements were included. SE progression over 3 years was analysed in non-myopic (SE ≥ + 0.76 D), pre-myopic (PM; ...


Comment on: Development and validation of a novel nomogram for predicting the o...

Lança, Carla; Parssinen, Olavi; Mehravaran, Shiva; Nordhausen, Klaus; Emamian, Mohammad Hassan; Grzybowski, Andrzej

In the recent article published by Guo et al., the authors used data from 2nd and 3rd graders to develop a nomogram to predict myopia onset in schoolchildren. Given that myopia can progress to high myopia, which is in turn a risk factor for pathologic myopia, prediction tools are timely and relevant. We would like to provide insights into other limitations and offer suggestions that can inform future works.


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