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Docetaxel-loaded folate-modified TPGS-transfersomes for glioblastoma multiforme...

Made available in DSpace on 2021-06-25T11:13:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Glioblastoma multiforme (GBM) is a first primary Central Nervous System tumor with high incidence and lethality. Its treatment is hampered by the difficulty to overcome the...

Influence of 1,3,5-triazine core and electron donor group in photophysical prop...

Exploiting the furo[2,3-b]pyridine core against multidrug-resistant Mycobacteri...

β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential ...

Palladium-catalyzed C–H alkenylation of quinoxaline N-oxide enabled by a mono-N...

Strategies towards expansion of chemical space of natural product‑based compoun...

Natural products (NPs) are an excellent source of biologically active molecules that provide many biologically biased features that enable innovative designing of synthetic compounds. NPs are characterized by high content of sp3 -hybridized carbon atoms; oxygen; spiro, bridged, and linked systems; and stereogenic centers, with high structural diversity. To date, several approaches have been implemented for mapp...

Oral administration of peptide-based drugs: beyond Lipinski's rule

Synthesis and photophysical properties of iron-carbonyl complex–coumarin conjug...

Charting the chemical reactivity space of 2,3-substituted furo[2,3-b]pyridines ...

Thiocyanation of BODIPY dyes and their conversion to thioalkylated derivatives