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The neuromicrobiology of Parkinson's disease: A unifying theory

Munoz-Pinto, Mario F.; Empadinhas, Nuno Miguel da Silva; Cardoso, Sandra M.

Recent evidence confirms that PD is indeed a multifactorial disease with different aetiologies and prodromal symptomatology that likely depend on the initial trigger. New players with important roles as triggers, facilitators and aggravators of the PD neurodegenerative process have re-emerged in the last few years, the microbes. Having evolved in association with humans for ages, microbes and their products are...


Pathways for the synthesis of mannosylglycerate in prokaryotes: genes, enzymes ...

Empadinhas, Nuno Miguel da Silva

Tese de doutoramento em Bioquímica (Microbiologia) apresentada à Fac. de Ciências e Tecnologia de Coimbra; Os microorganismos acumulam solutos compatíveis para ajustar a pressão intracelular, protegendo o metabolismo e viabilizando a sobrevivência do organismo em ambientes onde a salinidade ou a secura aumentaram. O manosilglicerato (MG) é um composto frequentemente encontrado em microorganismos de ambientes de...


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