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Co-assembled and microfabricated bioactive membranes
Mendes, A. C.; Smith, K. H.; Tejeda-Montes, E.; Engel, E.; Reis, R. L.; Azevedo, Helena S.; Mata, A.The fabrication of hierarchical and bioactive self-supporting membranes, which integrate physical and biomolecular elements, using a single-step process that combines molecular self-assembly with soft lithography is reported. A positively charged multidomain peptide (with or without the cell-adhesive sequence arginine-glycine-aspartic acid-serine (RGDS)) self-assembles with hyaluronic acid (HA), an anionic biop...
Date: 2013
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Origin: RepositóriUM - Universidade do Minho