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HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes :...
Cardeal, Laura Beatriz da Silva; Boccardo, Enrique; Termini, Lara; Rabachini, Tatiana; Andreoli, Maria Antonieta; Loreto, Celso di; Filho, A. L.Cervical cancer is the third most common cancer in women worldwide. Persistent infection with high-risk HPV types, principally HPV16 and 18 is the main risk factor for the development of this malignancy. However, the onset of invasive tumor occurs many years after initial exposure in a minority of infected women. This suggests that other factors beyond viral infection are necessary for tumor establishment and p...
Date: 2012
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Origin: RepositóriUM - Universidade do Minho