Made available in DSpace on 2021-06-25T11:10:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Universidade Estadual Paulista; Universidad Nacional Autónoma de México; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Histoplasma capsulatum affects healthy and immunocompromised individuals, sometimes causing a severe disease. This fungus has two morphotypes, the mycelial (infe...
Made available in DSpace on 2020-12-11T23:33:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01. Added 1 bitstream(s) on 2021-07-15T14:37:37Z : No. of bitstreams: 1 S0074-02762020000100334.pdf: 1976940 bytes, checksum: 45d01233b7ece2a2d5ff407e2012f283 (MD5); BACKGROUND Paracoccidioides spp. causes paracoccidioidomycosis (PCM), an important and frequent systemic mycosis that occurs in Latin America....
Made available in DSpace on 2019-10-06T16:52:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The fermentation process is widely used in the industry for bioethanol production. Even though it is widely used, microbial contamination is unpredictable and difficult to control. The problem of reduced productivity is directly linke...
Sirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously shown to modulate proteotoxicity associated with age-associated neurodegenerative disorders such as Alzheimer and Parkinson disease (PD). However, the precise molecular mechanisms involved remain unclear. Here, we provide mechanistic insight into the interplay between sirtuin 2 and α-synucl...