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Genetic Characteristics of Latvian Patients with Familial Hypercholesterolemia:...

Latkovskis, Gustavs; Rescenko-Krums, Raimonds; Nesterovics, Georgijs; Briviba, Monta; Saripo, Vita; Gilis, Dainus; Terauda, Elizabete; Meiere, Ruta

Background: There is limited data on the genetic characteristics of patients with familial hypercholesterolemia (FH) in Latvia. We aim to describe monogenic variants in patients from the Latvian Registry of FH (LRFH). Methods: Whole genome sequencing with 30 coverage was performed in unrelated index cases from the LRFH and the Genome Database of Latvian Population. LDLR, APOB, PCSK9, LDLRAP1, ABCG5, ABCG8, LIPA...


Stent-Save a Life international survey on the practice of primary percutaneous ...

Pereira, Helder; Naber, Christoph; Wallace, Sandrine; Gabor, Tóth; Abdi, Sayfollah; Alekyan, Bagrat; Alexander, Thomas; Artucio, Carolina

Aim: To assess the impact of the COVID-19 pandemic on admissions of patients with acute coronary syndromes (ACS) and primary percutaneous coronary intervention (PPCI) in countries participating in the Stent-Save a Life (SSL) global initiative. Methods and results: We conducted a multicenter observational survey to collect data on patient admissions for ACS, ST-elevation myocardial infarction (STEMI) and PPCI in...


European Society of Cardiology : cardiovascular disease statistics 2017

Timmis, Adam; Townsend, Nick; Gale, Chris; Grobbee, Rick; Maniadakis, Nikos; Flather, Marcus; Wilkins, Elizabeth; Wright, Lucy; Vos, Rimke; Bax, Jeroen

Aims: The European Society of Cardiology (ESC) Atlas has been compiled by the European Heart Agency to document cardiovascular disease (CVD) statistics of the 56 ESC member countries. A major aim of this 2017 data presentation has been to compare high-income and middle-income ESC member countries to identify inequalities in disease burden, outcomes, and service provision. Methods and results: The Atlas utilizes...


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