27 documents found, page 1 of 3
Nocardia nova causing empyema necessitatis afterlung re-transplantation: a case...
Severo,Cecília Bittencourt; Matter,Letícia Beatriz; Oliveira,Flávio de Mattos; Vargas,Agueda Palmira Castagna; Schio,Sadi MarceloAbstract: We report herein a case of thoracic infection due to Nocardia nova following lung re-transplantation performed for emphysema related to alpha-1-antitrypsin deficiency. The infection extended from the lung into the pleural space, thoracic wall, and mediastinum, presenting as pericarditis and empyema necessitatis. Nocardia nova was identified by 16S ribosomal deoxyribonucleic acid (rDNA) sequencing and ...
Antifungal activities of tacrolimus in combination with antifungal agents again...
Kubiça,Thaís Felli; Denardi,Laura Bedin; Azevedo,Maria Isabel; Oliveira,Vanessa; Severo,Luiz Carlos; Santurio,Janio Morais; Alves,Sydney HartzABSTRACT The antifungal activity of tacrolimus in combination with antifungal agents against different fungal species has been previously reported. Here we report the in vitro interactions between tacrolimus and amphotericin B, fluconazole, itraconazole, and caspofungin against 30 clinical isolates of both fluconazole-susceptible and fluconazole-resistant Trichosporon asahii. For these analyses, we used the bro...
The halo sign: HRCT findings in 85 patients
Alves,Giordano Rafael Tronco; Marchiori,Edson; Irion,Klaus; Nin,Carlos Schuler; Watte,Guilherme; Pasqualotto,Alessandro Comarú; Severo,Luiz CarlosABSTRACT Objective: The halo sign consists of an area of ground-glass opacity surrounding pulmonary lesions on chest CT scans. We compared immunocompetent and immunosuppressed patients in terms of halo sign features and sought to identify those of greatest diagnostic value. Methods: This was a retrospective study of CT scans performed at any of seven centers between January of 2011 and May of 2015. Patients wer...
Determination of germ tube, phospholipase, and proteinase production by bloodst...
Mattei,Antonella Souza; Alves,Sydney Hartz; Severo,Cecilia Bittencourt; Guazzelli,Luciana da Silva; Oliveira,Flavio de Mattos; Severo,Luiz CarlosIntroduction Candida albicans is a commensal and opportunistic agent that causes infection in immunocompromised individuals. Several attributes contribute to the virulence and pathogenicity of this yeast, including the production of germ tubes (GTs) and extracellular hydrolytic enzymes, particularly phospholipase and proteinase. This study aimed to investigate GT production and phospholipase and proteinase acti...
Histoplasmose simulando neoplasia primária de pulmão ou metástases pulmonares
Dall Bello,Aline Gehlen; Severo,Cecilia Bittencourt; Guazzelli,Luciana Silva; Oliveira,Flavio Mattos; Hochhegger,Bruno; Severo,Luiz CarlosOBJETIVO: Descrever as principais características clínico-radiológicas de pacientes com histoplasmose simulando câncer de pulmão. MÉTODOS: Estudo descritivo e retrospectivo baseado na análise dos prontuários médicos de 294 pacientes diagnosticados com histoplasmose no Laboratório de Micologia da Irmandade Santa Casa de Misericórdia de Porto Alegre, em Porto Alegre (RS), entre 1977 e 2011. O diagnóstico de histo...
Bola fúngica por Aspergillus fumigatus em cavidade pleural
Guazzelli,Luciana Silva; Severo,Cecília Bittencourt; Hoff,Leonardo Santos; Pinto,Geison Leonardo Fernandes; Camargo,José Jesus; Severo,Luiz CarlosOBJETIVO: Relatar os casos de 6 pacientes com bola fúngica (BF) na cavidade pleural por Aspergillus fumigatus. MÉTODOS: Entre 1980 e 2009, foram diagnosticados 391 pacientes com BF aspergilar no Complexo Hospitalar Santa Casa de Porto Alegre (RS). O diagnóstico de BF na cavidade pleural foi definido com exames de imagem demonstrando derrame e espessamento pleural com nível líquido; exame micológico direto demon...
Oropharyngeal histoplasmosis: report of eleven cases and review of the literature
Antonello,Vicente Sperb; Zaltron,Vanice Ferrazza; Vial,Marcela; Oliveira,Flávio Mattos de; Severo,Luiz CarlosINTRODUCTION: Histoplasmosis is a systemic mycosis endemic in Brazil, especially in the State of Rio Grande do Sul, where Histoplasma capsulatum was isolated from the soil. H. capsulatum may compromise unusual areas, including the oropharynx, particularly in patients presenting disseminated histoplasmosis; which is associated with a state of immunosuppression, such as AIDS. METHODS: During database analysis of ...
Capítulo 7 - Zigomicose
Severo,Cecília Bittencourt; Guazzelli,Luciana Silva; Severo,Luiz CarlosA zigomicose (mucormicose) é uma infecção rara, mas altamente invasiva, causada por fungos da ordem Mucorales (gêneros Rhizopus, Mucor, Rhizomucor, Absidia, Apophysomyces, Saksenaea, Cunninghamella, Cokeromyces e Syncephalastrum). Esse tipo de infecção é usualmente associado a doenças hematológicas, cetoacidose diabética e transplante de órgãos. A apresentação clínica mais frequente é a mucormicose rinocerebral...
Associação entre paracoccidioidomicose e câncer
Rodrigues,Gustavo da Silva; Severo,Cecília Bittencourt; Oliveira,Flávio de Mattos; Moreira,José da Silva; Prolla,João Carlos; Severo,Luiz CarlosOBJETIVO: Analisar a associação entre paracoccidioidomicose (Pcm) e câncer e realizar uma revisão da literatura sobre esse tópico. MÉTODOS: Revisão retrospectiva de 25 casos diagnosticados com Pcm e câncer, extraídos de uma série de 808 casos consecutivos de pacientes adultos diagnosticados com Pcm com base nos testes realizados no Laboratório de Micologia da Santa Casa Complexo Hospitalar de Porto Alegre (RS),...
Galactomannan detection from piperacillin-tazobactam brands available in the Br...
Xavier,Melissa Orzechowski; Pasqualotto,Alessandro Comarú; Aquino,Valério Rodrigues; Sukiennik,Teresa Cristina Teixeira; Severo,Luiz CarlosPiperacillin-tazobactam is a broad spectrum antimicrobial agent that can cause false-positive results in the commercial Platelia Aspergillus EIA test. So far, no study has been performed in Latin America to evaluate the clinical implication of this finding. Here we studied the potential for galactomannan detection in piperacillin-tazobactam batches commercialized in the Brazilian market. Five batches from disti...