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Gynecological History Up to Diagnosis and Pregnancy Outcomes in Diagnosed Wilso...

Roseira, J; Lopes, R; Silva, MJ; Vieira, AM; Sampaio, M; Calinas, F

Introduction: most studies narrowly focus on pregnancy outcome comparisons between Wilson’s disease (WD) patients on and off treatment. We aimed to identify menses irregularities in untreated WD, and to evaluate pregnancy outcomes in treated WD patients as compared to matched controls (with and without liver disease). Methods: females with WD, hepatitis C (liver disease controls), and other gastrointestinal con...


A Narrative Review on Anti-Tumor Necrosis Factor α Therapies in Inflammatory Bo...

Roseira, J; Ramos, J

INTRODUCTION: Inflammatory bowel disease activity is associated with adverse pregnancy outcomes. Anti-tumor necrosis factor α therapy is often required to treat flares and to maintain disease remission. However, there are concerns regarding treatment with these agents during pregnancy, as they actively cross the placental barrier. MATERIAL AND METHODS: Studies regarding anti-tumor necrosis factor α therapy duri...


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