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In silico analysis of plant microRNAs and their targets in public database of P...

Costa Filho, Ailton Pereira da; Cançado, Fernando Augusto Corrêa Queiroz; Alves, Tamires Caixeta; Espíndola, Foued Salmen; Amaral, Laurence Rodrigues do

Post-traumatic stress disorder (PTSD) refers to simultaneous appearance of intrusions, avoidance, negative cognitions, and hyperarousal, triggered by traumatic events. It’s a psychiatric illness highly comorbid with depression whose roots are unknown, although gene expression profile has shown to be linked with environment, providing molecular tips about stress diseases. Mature miRNAs are small non-coding RNAs ...

Date: 2019   |   Origin: Oasisbr

The higher exercise intensity and the presence of allele I of ACE gene elicit a...

Santana, Hugo Alexandre de Paula; Moreira, Sérgio Rodrigues; Botelho Neto, Willson; Silva, Carla Britto da; Sales, Marcelo Magalhães de

Background The absence of the I allele of the angiotensin converting enzyme (ACE) gene has been associated with higher levels of circulating ACE, lower nitric oxide (NO) release and hypertension. The purposes of this study were to analyze the post-exercise salivary nitrite (NO2-) and blood pressure (BP) responses to different exercise intensities in elderly women divided according to their ACE genotype. Methods...

Date: 2012   |   Origin: Oasisbr

Inibição de metaloproteinases por extratos aquosos de aloe vera, annona muricat...

Ribeiro, Rosy Iára Maciel A.; Sayuri Kuribayashi, Juliana; Borges Júnior, Paulo Cesar; Beletti, Marcelo Emílio; Espíndola, Foued Salmen

As Metaloproteinases de Matriz (MMPs) podem exercer importantes funções na remodelagem fisiológica e patológica da matriz extracelular. Elas são implicadas na progressão tumoral de muitas malignidades humanas interferindo em eventos angiogênicos, invasivos e metastáticos. Produtos obtidos de algumas plantas têm sido consistentemente associados a funções neoplásicas, possivelmente por reproduzir a atividade neut...

Date: 2010   |   Origin: Oasisbr

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