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Recent advances in nanomaterial-based optical biosensors for food safety applic...

Meira, Diana I.; Barbosa, Ana Isabel Ferreira; Borges, Joel; Reis, R. L.; Correlo, V. M.; Vaz, Filipe

Global population growth tremendously impacts the global food industry, endangering food safety and quality. Mycotoxins, particularly Ochratoxin-A (OTA), emerge as a food chain production threat, since it is produced by fungus that contaminates different food species and products. Beyond this, OTA exhibits a possible human toxicological risk that can lead to carcinogenic and neurological diseases. A selective, ...


Immobilization of Streptavidin on a Plasmonic Au-TiO2 Thin Film towards an LSPR...

Pereira-Silva, Patrícia; Meira, Diana I.; Costa-Barbosa, Augusto; Costa, Diogo; Rodrigues, Marco S.; Borges, Joel; Machado, Ana V.; Cavaleiro, Albano

Optical biosensors based on localized surface plasmon resonance (LSPR) are the future of label-free detection methods. This work reports the development of plasmonic thin films, containing Au nanoparticles dispersed in a TiO2 matrix, as platforms for LSPR biosensors. Post-deposition treatments were employed, namely annealing at 400 °C, to develop an LSPR band, and Ar plasma, to improve the sensitivity of the Au...


Optimization of Au:CuO thin films by plasma surface modification for high-resol...

Proença, Manuela; Rodrigues, Marco S.; Meira, Diana I.; Castro, M. Cidalia R.; Rodrigues, Pedro V.; Machado, A. V.; Alves, Eduardo; Barradas, Nuno P.

In this study, thin films composed of gold nanoparticles embedded in a copper oxide matrix (Au:CuO), manifesting Localized Surface Plasmon Resonance (LSPR) behavior, were produced by reactive DC magnetron sputtering and post-deposition in-air annealing. The effect of low-power Ar plasma etching on the surface properties of the plasmonic thin films was studied, envisaging its optimization as gas sensors. Thus, t...


Immobilization of streptavidin on a plasmonic Au-TiO2 thin film towards an LSPR...

Pereira-Silva, Patrícia; Meira, Diana I.; Costa-Barbosa, Augusto; Costa, Diogo; Rodrigues, Marco S.; Borges, Joel; Machado, Ana V.; Cavaleiro, Albano

Optical biosensors based on localized surface plasmon resonance (LSPR) are the future of label-free detection methods. This work reports the development of plasmonic thin films, containing Au nanoparticles dispersed in a TiO<sub>2</sub> matrix, as platforms for LSPR biosensors. Post-deposition treatments were employed, namely annealing at 400 °C, to develop an LSPR band, and Ar plasma, to improve the sensitivit...


Preparation of plasmonic Au-TiO2 thin films on a transparent polymer substrate

Rodrigues, Marco S.; Meira, Diana I.; Lopes, Cláudia; Borges, Joel; Vaz, F.

In this work, plasmonic thin films composed of Au nanoparticles embedded in a TiO<sub>2</sub> matrix were prepared in a transparent polymer substrate of poly(dimethylsiloxane) (PDMS). The thin films were deposited by reactive DC magnetron sputtering, and then subjected to heat treatment up to 150 °C in order to promote the growth of the Au nanoparticles throughout the TiO<sub>2</sub> matrix. The transmittance s...


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