11 documents found, page 1 of 2
Hyptis pectinata gel prevents alveolar bone resorption in experimental periodon...
Paixão,Mônica S.; Melo,Mônica S.; Damascena,Nicole P.; Araújo,Adriano A.S.; Soares,Andrea F.; Oliveira,Denise V.A.; Oliveira,Jeison S.Hyptis pectinata (L.) Poit., Lamiaceae, is an aromatic, abundant and broadly used plant species in Sergipe to treat oral and gastrointestinal pain and inflammation. The aim of the present study was to analyze the relation between periodontitis and changes in the corporal mass and alveolar bone structure after induction of experimental periodontal disease in rat treated or not treated with H. pectinata gel at 5%...
Phytochemical study and antinociceptive effect of the hexanic extract of leaves...
Quintans,Jullyana S.S.; Costa,Emmanoel V.; Tavares,Josean F.; Souza,Thais T.; Araújo,Silvan S.; Estevam,Charles S.; Barison,AnderssonCombretum duarteanum Cambess, Combretaceae, is a plant widely distributed in Northeastern Brazil and, in folk medicine, stems and leaves are used for pain treatment. We investigated the antinociceptive effects of the hexanic extract of leaves from C. duarteanum and of friedelin, its main compound, in formalin-, glutamate- and capsaicin- induced orofacial nociception models. In order to isolate friedelin from th...
Evaluation of the toxicity and molluscicidal and larvicidal activities of Schin...
Santos,Clisiane C.S.; Araújo,Silvan S.; Santos,André L.L.M.; Almeida,Elis C.V.; Dias,Antônio S.; Damascena,Nicole P.; Santos,Deisylaine M.Dengue fever and schistosomiasis are major public health issues for which vector control using larvicide and molluscicide substances present in plants provides a promising strategy. This study evaluated the potential toxicity of the extract of hydroethanol Schinopsis brasiliensis Engl., Anacardiaceae, stem bark and its chloroform, hexane, ethyl acetate, and hydromethanol fractions against Artemia salina and Aed...
Investigation of protective effects of Erythrina velutina extract against MMS i...
Silva,Deborah S. B. S.; Barboza,Benhur; Garcia,Anuska C. F. S.; Oliveira,Betejane de; Estevam,Charles S.; A. Neto,Vitor; Santos,Andre L. L. M.Erythrina velutina Willd., Fabaceae, is a medicinal plant that can be found in the tropics and subtropics, including in the semi-arid northeastern Brazil. It is commonly used in folk medicine to treat anxiety, agitation and insomnia. E. velutina has been known to present analgesic, anti-inflammatory and antibacterial activities, however, it is unknown if this plant present a protective effect on DNA. We assesse...
Genotoxicity test of Maytenus rigida and Aristolochia birostris in the radicula...
Mendes,Sandra S.; Andrade,Josivaldo A.; Xavier,Maria Aldirene; Secundo Junior,José A.; Pantaleão,Silmara M.; Estevam,Charles S.; Garcia,Carlos A.B.Medicinal plants are an important source of treatment for many ailments, although little is known of the potential genotoxic effects of most species. In the present study, two species from diverse and medicinally important genera - Maytenus rigida Mart., Celastraceae, and Aristolochia birostris Ducht, Aristolochiaceae - were analyzed to identify potentially significant secondary metabolites and the possible eff...
Genotoxicity and cytotoxicity of Erythrina velutina Willd., Fabaceae, on the ro...
Silva,Déborah S. B. S.; Garcia,Anuska C. F. S.; Mata,Samuel S.; Oliveira,Betejane de; Estevam,Charles S.; Scher,Ricardo; Pantaleao,Silmara M.The effects of the decoction of Erythrina velutina Willd., Fabaceae, were investigated using the root meristem cells of Allium cepa L., Amaryllidaceae. Ten concentrations of the aqueous extract (0.125 to 1.25%) of this medicinal plant were analyzed at both macroscopic and microscopic levels. All concentrations showed root growth inhibition after 96 h treatment. Although there were no significant differences bet...
Antinociceptive and anti-inflammatory effects of Caesalpinia pyramidalis in rod...
Santos,Cliomar A.; Passos,Ailane M. P. R.; Andrade,Fernando C.; Camargo,Enilton A.; Estevam,Charles S.; Santos,Márcio R. V.; Thomazzi,Sara M.Caesalpinia pyramidalis Tul., Fabaceae, is a plant with an anti-inflammatory activity that is used in folk medicine. To evaluate the mechanism of action of this plant, studies were performed on its antinociceptive and anti-inflammatory properties using an ethanol extract (EE) made from the inner bark. Oral treatment of mice with the EE (100, 200, and 400 mg/kg) decreased their acetic acid-induced abdominal writ...
Preliminary study on the anti-inflammatory and antioxidant activities of the le...
Andrade,Alexandre M.; Oliveira,Juliana P. R.; Santos,André L. L. M.; Franco,Clóvis R. P.; Antoniolli,Ângelo R.; Estevam,Charles S.; Thomazzi,Sara M.Various species of Hyptis are used in folk medicine as anti-inflammatory. In order to evaluate the actions of Hyptis fruticosa Salzm. ex Benth., Lamiaceae, studies were performed on anti-inflammatory and antioxidant activities. The ethanol extract (EE) of H. fruticosa leaves and its n-CH, CHCl, EtOAc, and MeOH/HO partitions were used in the following experiments. Oral treatment with the EE of H. fruticosa leave...
Perfil fitoquímico e ensaio microbiológico dos extratos da entrecasca de Mayten...
Estevam,Charles S.; Cavalcanti,Amaro M.; Cambui,Érica Verena F.; Araújo Neto,Vítor; Leopoldo,Paulo T. G.; Fernandes,Roberta P. M.Maytenus rigida Mart (Celastraceae), conhecida por "Bom-homem", "Bom-nome", "Cabelo-de-negro", "Casca-grossa" e "Pau-de-colher", é uma arvore de pequeno porte. A entrecasca do caule é empregada popularmente no Nordeste do Brasil no tratamento das dores em geral, infecções e inflamações. O presente trabalho avaliou tanto o perfil fitoquímico de M. rigida por meio de um roteiro analítico, quanto à atividade antib...
Effects of the aqueous extract from Hyptis pectinata leaves on rodent central n...
Bueno,Alexsandro X.; Moreira,Alisson T.S.; Silva,Flávia T.; Estevam,Charles S.; Marchioro,MuriloThe effects of the aqueous extract (AE) from Hyptis pectinata leaves was studied on rodent central nervous system (CNS). Pharmacological screening, open field, forced swimming, apomorphine-induced hypothermia, elevated plus maze and thiopental-induced sleep tests were used in male and female Swiss mice and Wistar rats. The AE was admnistered orally in single doses 30 minutes before each test. In the screening t...