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Impact of post-COVID-19 condition on health status and functional capacity: a c...

Pereira, Andreia; Amaral, Luísa; Dias, Inês; Magalhães, André; Abreu, Verónica; Esteves, Mário; Vilarinho, Rui; Cervaens, Mariana; Vilarinho, Rui

To assess health status and functional capacity in adults with post-COVID-19 condition. Observational, retrospective cross-sectional study. Outpatients from the Physical Medicine and Rehabilitation Department of the Hospital Fernando Pessoa, Porto, Portugal, were included. A convenient sample included 54 participants aged over 18 years old (52.4 6 15.5 years, 61% female), with diagnosis of SARS-CoV-2 infection ...


Portuguese translation, cultural adaptation and psychometric properties of the ...

Cervaens, Mariana; Vilarinho, Rui; Pereira, Jéssica; Magalhães, André; Esteves, Mário; Vilarinho, Rui; Abreu, Verónica; Amaral, Luísa

The temporomandibular joint (TMJ) scale assesses the severity of temporomandibular joint disorders (TMD), yet a European Portuguese translation is lacking. To translate, cross-culturally adapt and to examine the psychometric properties (construct validity and reliability) of the TMJ scale. Translation and cultural adaptation were carried out according to international recommendations, including initial translat...


Seronegative Autoimmune Hepatitis / Primary Biliary Cholangitis Overlap Syndrom...

Coutinho, Andreia; Soares, Cecília; Cardoso, João; Leão, Jorge; Iglesias, Violeta; Esteves, Mário

Continua por esclarecer se a síndrome de sobreposição representa uma variante da colangite biliar primária, da hepatite autoimune ou uma entidade clínica distinta. No presente artigo,apresentamos um caso clínico, delineando a marcha diagnóstica e a abordagem terapêutica de uma doente diagnosticada com esta patologia. Trata-se de uma mulher caucasiana de 64 anos, cujas manifestações clínicas abrangem característ...


A SUSPICIOUS CASE OF HEART DYSFUNCTION

Torres Marcos, David; Ventura, Ludovic; Portela, Raquel; Esteves, Mário; Leitão, Laurinda

Introduction: Amyloid fibrils are polymers of proteins involved in various physiological processes. When there is an accumulation of defective amyloid fibrils, a condition called amyloidosis occurs. This can have several subtypes.Case Report: The authors report a case of a 78-year-old male, independent in his daily life, came to the medical center complaining of aggravating dyspnea in the last months. He has co...


Fahr`s syndrome – apropos of a clinical case

Salomão, Jorge; Bandeira, Paulo; Esteves, Mário

Fahr’s Syndrome is a rare degenerative neurological disorder, which can be of hereditary or sporadic origin, characterized by the presence of abnormal calcium deposits and associated cell loss in certain areas of the brain, namely basal ganglia and cerebral cortex. Associated symptoms include progressive deterioration of cognitive abilities (dementia) and loss of acquired motor skills, speech impairment, seizur...


Avaliação da qualidade de vida relacionada com a saúde na Doença Pulmonar Obstr...

Esteves, Mário; Viana, Rui

A Qualidade de Vida Relacionada com a Saúde (QVRS) tem sido estudada na Doença Pulmonar Obstrutiva Crónica (DPOC). Avaliou-se a QVRS em 20 pacientes com DPOC e correlacionou-se o St George’s Respiratory Questionnaire (SGRQ) e o The Medical Outcomes Study Short Form 36 (SF-36) através do Coeficiente de Correlação de Pearson, cujo nível de significância estatística foi de 0,01. Aplicou-se o SGRQ, SF-36, Escala de...


Antioxidant Versus Cytotoxic Properties of Hydroxycinnamic Acid Derivatives - A...

Esteves, Mário; Siquet, Christophe; Gaspar, Alexandra; Rio, Vitor; Sousa, Joana B.; Reis, Salette; Marques, M. Paula M.; Borges, Fernanda

Trihydroxycinnamic derivatives were synthesized and evaluated for their antioxidant and cytotoxic activities. The ester derivatives exhibited a higher radical-scavenging activity, when liposomes were used as target systems, a fact which may be related to their lipophilicity and conformational preferences. These compounds were found to display significant growth inhibition and cytotoxic effects towards a human c...


Voltammetric and DFT Studies on Viloxazine: Analytical Application to Pharmaceu...

Garrido, E. Manuela P. J.; Garrido, Jorge M. P. J.; Esteves, Mário; Santos-Silva, Alice; Marques, M. Paula M.; Borges, Fernanda

The oxidative behavior of viloxazine was studied at a glassy carbon electrode in different buffer systems using cyclic, differential pulse and square-wave voltammetry. The oxidation process was shown to be diffusion-controlled and irreversible over the studied pH. The voltammetric study of the model compounds, 2-ethoxyanisole and morpholine, associated with quantum mechanical (DFT) calculations, allowed to eluc...


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