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Building a Portuguese coalition for biodiversity genomics

Marques, João P.; Alves, Paulo C.; Amorim, Isabel R.; Lopes, Ricardo J.; Moura, Monica; Myers, Eugene; Sim-sim, Manuela; Sousa-Santos, Carla

The diverse physiography of the Portuguese land and marine territory, spanning from continental Europe to the Atlantic archipelagos, has made it an important repository of biodiversity throughout the Pleistocene glacial cycles, leading to a remarkable diversity of species and ecosystems. This rich biodiversity is under threat from anthropogenic drivers, such as climate change, invasive species, land use changes...


Building a Portuguese coalition for biodiversity genomics

Marques, João P.; Alves, Paulo C.; Amorim, Isabel R.; Lopes, Ricardo Jorge; Moura, Monica; Myers, Eugene; Sim-Sim, Maria; Sousa-Santos, Carla

The diverse physiography of the Portuguese land and marine territory, spanning from continental Europe to the Atlantic archipelagos, has made it an important repository of biodiversity throughout the Pleistocene glacial cycles, leading to a remarkable diversity of species and ecosystems. This rich biodiversity is under threat from anthropogenic drivers, such as climate change, invasive species, land use changes...


The potential role of scavenging flies as mechanical vectors of Lagovirus europ...

Lopes, Ana M.; Almeida, Tereza; Diz, Sílvia; Côrte-Real, João V.; Osório, Hugo; Ramilo, David W.; Rebelo, Maria Teresa; Pereira da Fonseca, Isabel

The European rabbit (Oryctolagus cuniculus) populations of the Iberian Peninsula have been severely affected by the emergence of the rabbit haemorrhagic disease virus (RHDV) Lagovirus europaeus/GI.2 (RHDV2/b). Bushflies and blowflies (Muscidae and Calliphoridae families, respectively) are important RHDV vectors in Oceania, but their epidemiological role is unknown in the native range of the European rabbit. In ...


Brain and testis: more alike than previously thought?

Matos, Bárbara; Publicover, Stephen J.; Castro, Luis Filipe C.; Esteves, Pedro J.; Fardilha, Margarida

Several strands of evidence indicate the presence of marked similarities between human brain and testis. Understanding these similarities and their implications has become a topic of interest among the scientific community. Indeed, an association of intelligence with some semen quality parameters has been reported and a relation between dysfunctions of the human brain and testis has also been evident. Numerous ...


Evolutionary Insights into IL17A in Lagomorphs

Neves, Fabiana; Abrantes, Joana; Almeida, Tereza; Costa, Paulo P.; Esteves, Pedro J.

In leporids, IL17A had been implicated in the host defense against extracellular pathogens, such as Francisella tularensis that infects hares and rabbits and causes the zoonotic disease tularemia. Here, we studied IL17A from five lagomorphs, European rabbit, pygmy rabbit, brush rabbit, European brown hare, and American pika. We observed that this protein is highly conserved between these species, with a similar...


The phylogeny of pikas (Ochotona) inferred from a multilocus coalescent approach

Melo-Ferreira, José; Lemos de Matos, Ana; Areal, Helena; Lissovsky, Andrey A.; Carneiro, Miguel; Esteves, Pedro J.

The clarification of the systematics of pikas (genus Ochotona) has been hindered by largely overlapping morphological characters among species and the lack of a comprehensive molecular phylogeny. Here we estimate the first multilocus phylogeny of the genus to date, by analysing 12 nuclear DNA markers (total of 7.5 Kb) in 11 species of pikas from the four classified subgenera (Pika, Ochotona, Lagotona and Conoth...


Cross-species comparison of mammalian saliva using an LC-MALDI based proteomic ...

Sousa-Pereira, Patrícia de; Cova, Marta; Abrantes, Joana; Ferreira, Rita Maria Pinho; Trindade, Fábio; Barros, António; Gomes, Pedro de Sousa

Date: 2015   |   Origin: Repositório da UTAD

Evolution of C, D and S-Type Cystatins in Mammals: An Extensive Gene Duplicatio...

Pereira, Patrícia de Sousa; Abrantes, Joana; Pinheiro, Ana; Vitorino, Rui; Esteves, Pedro J.; Munderloh, Ulrike G.; Colaço, Bruno

Date: 2014   |   Origin: Repositório da UTAD

Not so pseudo: the evolutionary history of protein phosphatase 1 regulatory sub...

Korrodi-Gregório, Luís; Abrantes, Joana; Muller, Thorsten; Melo-Ferreira, José; Marcus, Katrin; Silva, Odete A. B. da Cruz e; Fardilha, Margarida

Background: Pseudogenes are traditionally considered “dead” genes, therefore lacking biological functions. This view has however been challenged during the last decade. This is the case of the Protein phosphatase 1 regulatory subunit 2 (PPP1R2) or inhibitor-2 gene family, for which several incomplete copies exist scattered throughout the genome. Results: In this study, the pseudogenization process of PPP1R2 was...


Characterization of thymosin ß4 in mammals’ saliva

Sousa-Pereira, Patrícia de; Abrantes, Joana; Castagnola, Massimo; Amado, Francisco; Esteves, Pedro J.; Vitorino, Rui; Colaço, Bruno

Date: 2013   |   Origin: Repositório da UTAD

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