9 documents found, page 1 of 1

Stereotactic body radiotherapy in primary lung disease: Experience of a portugu...

Background: Stereotactic body radiation therapy (SBRT) is the primary alternative to surgery for patients with clinical stage I or II non -small cell lung cancer (NSCLC) who have significant comorbidity that precludes safe resection and for those who refuse surgery. Methods: Patients with clinical stage I or II NSCLC treated with SBRT in our institution between January 2015 and December 2019 were retrospectivel...

Adjuvant Chemotherapy De-Escalation with Genomic Assay Protocol in Patients wit...

Introduction: Genomic assays are useful tools for tailoring adjuvant treatment in early breast cancer. We aimed to analyse the role of an institutional protocol of a genomic assay for chemotherapy de-escalation.Methods: Prospective cohort study of all consecutive women diagnosed with hormone receptor-positive and human epidermal growth factor receptor 2-negative early breast cancer, tested with the 21-gene Recu...

Distribution and Clinical Significance of HPV16 Variants in Head and Neck Squam...

Introduction: Genomic variants of the human papillomavirus type 16 (HPV16) are thought to play differential roles in the susceptibility to head and neck squamous cell carcinomas (HNSCC) and its biological behaviour. This study aimed to establish the prevalence of HPV16 variants in an HNSCC cohort and associate them with clinical pathological characteristics and patient survival. Methods: We retrieved samples an...

How Allogeneic Hematopoietic Stem Cell Transplantation has Evolved Over Time: 3...

Introduction: Allogeneic stem cell transplantation is an established procedure for a variety of diseases of the hematopoietic system. Our transplant program started in 1987 and since then advances have been made in the care of patients undergoing transplantation. We conducted a study to evaluate whether the changes implemented over time have improved the outcomes of transplantation.Material and Methods: We anal...

Screening for distress in BRCA1/2 carriers: a prospective study

Introdution: The period of time elapsed after receiving a positive test result, has been previously associated with distress in BRCA1/2 carriers. However, there is a need for reliable instruments and prospective data on distress and perception of risk by those carriers, given the significant increase in demand for BRCA1/2 testing. &...

Os pais e a hospitalização do recém-nascido permaturo.

Autonomia profissional e complementaridade funcional em enfermagem.

Sexualidade na gravidez: problema ou solução?

Anorexia nervosa: o outro lado do espelho.