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Evaluation of behavioral and neuroprotective effects of losartan in diabetic rats

Silva, Joana; Teixeira, Fábio; Esteves-Monteiro, Marisa; Araújo, Margarida; Magalhães, Ana

Diabetes is known to negatively impact the brain, leading to memory loss and attention issues [1], as well as an increased incidence of depression, cognitive impairment, and behavioral changes. Recent studies indicate that angiotensin II AT1 receptor antagonists (ARAs) may reduce depressive symptoms, however, the mechanism of action is not yet fully understood [2]. The aim of the present study was to verify whe...


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