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Assessment of Continuous Pain in Newborns Admitted to NICUs in 18 European Coun...

Anand, K; Eriksson, M; Boyle, E; Avila-Alvarez, A; Andersen, R; Sarafidis, K; Polkki, T; Matos, C; Lago, P; Papadouri, T; Attard-Montalto, S; Ilmoja, ML

AIM: Continuous pain occurs routinely, even after invasive procedures, or inflammation and surgery, but clinical practices associated with assessments of continuous pain remain unknown. METHODS: A prospective cohort study in 243 neonatal intensive care units (NICUs) from 18 European countries recorded the frequency of pain assessments, use of mechanical ventilation, sedation, analgesia or neuromuscular blockade...


Use of evidence based practices to improve survival without severe morbidity fo...

Zeitlin, J; Manktelow, BN; Piedvache, A; Cuttini, M; Boyle, E; van Heijst, A; Gadzinowski, J; van Reempts, P; Huusom, L; Weber, T; Schmidt, S; Barros, H

Objectives To evaluate the implementation of four high evidence practices for the care of very preterm infants to assess their use and impact in routine clinical practice and whether they constitute a driver for reducing mortality and neonatal morbidity. Design Prospective multinational population based observational study. Setting 19 regions from 11 European countries covering 850 000 annual births participati...


Authors' reply to Page and Rafi

Zeitlin, J; Manktelow, BN; Piedvache, A; Cuttini, M; Boyle, E; Van Heijst, A; Gadzinowski, J; Van Reempts, P; Huusom, L; Weber, T; Schmidt, S; Barros, H


Sedation and Analgesia Practices in Neonatal Intensive Care Units (EUROPAIN): R...

Carbajal, R; Eriksson, M; Boyle, E; Avila-Alvarez, A; Dovland Andersen, R; Sarafidis, K; Polkki, T; Matos, C; Lago, P; Papadouri, T; Attard Montalto, S

BACKGROUND: Neonates who are in pain or are stressed during care in the intensive care unit (ICU) are often given sedation or analgesia. We investigated the current use of sedation or analgesia in neonatal ICUs (NICUs) in European countries. METHODS: EUROPAIN (EUROpean Pain Audit In Neonates) was a prospective cohort study of the management of sedation and analgesia in patients in NICUs. All neonates admitted t...


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